Divergent Annulative C-C Coupling of Indoles Initiated by Manganese-Catalyzed C-H Activation
文献类型：期刊论文
| 作者 | Li, Xingwei1,2; Liu, Bingxian2; Li, Jie2; Hu, Panjie2; Zhou, Xukai1; Bai, Dachang2 |
| 刊名 | ACS CATALYSIS
 |
| 出版日期 | 2018-10-01 |
| 卷号 | 8期号:10页码:9463-9470 |
| 关键词 | manganese catalysis condition control indole C-H activation enyne |
| ISSN号 | 2155-5435 |
| DOI | 10.1021/acscatal.8b02560 |
| 通讯作者 | Li, Xingwei(xwli@dicp.ac.cn) |
| 英文摘要 | Manganese(I)-catalyzed C-H activation of indoles and divergent annulative coupling with alkyne-tethered cyclohexadienones has been realized under operationally simple conditions. These annulation systems are under condition control. The coupling in the presence of BPh3 additive followed a C-H activation-alkyne insertion-Michael addition pathway, affording an exocyclic olefin attached to a tetrahydrofuran ring. In contrast, when Zn(OAc)(2)/PivOH additives were introduced, initial olefination en route to intramolecular Diels-Alder reaction and subsequent elimination of an alcohol was followed to deliver a fused six-membered ring. The selectivity stands in contrast to those reported using rhodium(III) and cobalt(III) catalysts, highlighting the unique reactivity and selectivity of manganese catalysts. |
| WOS关键词 | DIELS-ALDER REACTIONS ; BOND FUNCTIONALIZATION ; ARYLATIVE CYCLIZATION ; ORGANIC-SYNTHESIS ; DIRECTING GROUPS ; DRUG DISCOVERY ; BRIDGED CYCLES ; ALLENES ; ALKYNES ; ACCESS |
| 资助项目 | NSFC[21525208] ; NSFC[21472186] ; Henan Normal University[5101034011009] ; Henan Normal University[qd16111] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000447224100056 |
| 出版者 | AMER CHEMICAL SOC |
| 资助机构 | NSFC ; NSFC ; Henan Normal University ; Henan Normal University ; NSFC ; NSFC ; Henan Normal University ; Henan Normal University ; NSFC ; NSFC ; Henan Normal University ; Henan Normal University ; NSFC ; NSFC ; Henan Normal University ; Henan Normal University |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/166830]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Li, Xingwei |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Henan Normal Univ, Sch Chem & Chem Engn, Henan Key Lab Organ Funct Mol & Drug Innovat, Xinxiang 453007, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Xingwei,Liu, Bingxian,Li, Jie,et al. Divergent Annulative C-C Coupling of Indoles Initiated by Manganese-Catalyzed C-H Activation[J]. ACS CATALYSIS,2018,8(10):9463-9470. |
| APA | Li, Xingwei,Liu, Bingxian,Li, Jie,Hu, Panjie,Zhou, Xukai,&Bai, Dachang.(2018).Divergent Annulative C-C Coupling of Indoles Initiated by Manganese-Catalyzed C-H Activation.ACS CATALYSIS,8(10),9463-9470. |
| MLA | Li, Xingwei,et al."Divergent Annulative C-C Coupling of Indoles Initiated by Manganese-Catalyzed C-H Activation".ACS CATALYSIS 8.10(2018):9463-9470. |
入库方式： OAI收割
来源：大连化学物理研究所
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