Oriented surface epitope imprinted polymer-based quartz crystal microbalance sensor for cytochrome c
文献类型：期刊论文
| 作者 | He, Xi-Wen2; Zhang, Yu-Kui2,3; Ma, Xiao-Tong2; Li, Wen-You1,2 |
| 刊名 | TALANTA
 |
| 出版日期 | 2019 |
| 卷号 | 191页码:222-228 |
| 关键词 | Quartz crystal microbalance sensor Chemosensing Protein recognition Oriented epitope imprinted polymers Reverse microemulsion polymerization |
| ISSN号 | 0039-9140 |
| DOI | 10.1016/j.talanta.2018.08.079 |
| 通讯作者 | Li, Wen-You(wyli@nankai.edu.cn) |
| 英文摘要 | A quartz crystal microbalance (QCM) sensor for detecting cytochrome c based on an oriented surface epitope imprinted polymer was fabricated in this paper. By using the palmitic acid-modified epitope of cytochrome c as the template and the 3-aminopropyltriethoxysilane as the monomer, we prepared a new oriented surface epitope imprinted polymer by the reverse microemulsion polymerization. The prepared oriented imprinted polymer had better imprinting effect than the non-oriented imprinted polymer. And compared to previous studies, this polymerization method is simple and could be carried out at room temperature in the presence of oxygen, under regular atmospheric conditions. Then, by combining the advantages of molecularly imprinted polymers and QCM sensors, we used the prepared polymer to establish a QCM sensor. The described sensor showed good sensitivity and selectivity towards cytochrome c. The linear range was from 0.005 mu g mL(-1) to 0.050 mu g mL(-1) and the detection limit was 3.6 ng mL(-1) which is lower than most of previous works. Besides, it could be used for real sample analysis and had satisfactory reproducibility and accuracy. This work proposed a new way of fabricating oriented surface epitope imprinted polymers-based QCM sensors for selectively detecting proteins at very low concentrations. |
| WOS关键词 | SELECTIVE DETERMINATION ; NANOPARTICLES ; PROTEIN ; RECOGNITION ; AFFINITY ; PERSPECTIVES ; NANOSENSOR ; RECEPTOR ; FILM |
| 资助项目 | National Natural Science Foundation of China[21275078] ; National Natural Science Foundation of China[21475069] ; National Natural Science Foundation of China[21775077] ; Tianjin Natural Science Foundation[16JCZDJC37200] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000447481600029 |
| 出版者 | ELSEVIER SCIENCE BV |
| 资助机构 | National Natural Science Foundation of China ; National Natural Science Foundation of China ; Tianjin Natural Science Foundation ; Tianjin Natural Science Foundation ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Tianjin Natural Science Foundation ; Tianjin Natural Science Foundation ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Tianjin Natural Science Foundation ; Tianjin Natural Science Foundation ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Tianjin Natural Science Foundation ; Tianjin Natural Science Foundation |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/166858]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Li, Wen-You |
| 作者单位 | 1.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China 2.Nankai Univ, Tianjin Key Lab Biosensing & Mol Recognit, Coll Chem, Res Ctr Analyt Sci,State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Xi-Wen,Zhang, Yu-Kui,Ma, Xiao-Tong,et al. Oriented surface epitope imprinted polymer-based quartz crystal microbalance sensor for cytochrome c[J]. TALANTA,2019,191:222-228. |
| APA | He, Xi-Wen,Zhang, Yu-Kui,Ma, Xiao-Tong,&Li, Wen-You.(2019).Oriented surface epitope imprinted polymer-based quartz crystal microbalance sensor for cytochrome c.TALANTA,191,222-228. |
| MLA | He, Xi-Wen,et al."Oriented surface epitope imprinted polymer-based quartz crystal microbalance sensor for cytochrome c".TALANTA 191(2019):222-228. |
入库方式： OAI收割
来源：大连化学物理研究所
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