Novel N-chloramine precursors for antimicrobial application: synthesis and facile covalent immobilization on polyurethane surface based on perfluorophenyl azide (PFPA) chemistry
文献类型：期刊论文
| 作者 | Gai, Fangyuan4; Wang, Hande3; Li, Lingdong3; Chi, Xiaofang; Zhang, Fengxiang3; Zhou, Hao1; Zhao (Kent), Zongbao2 |
| 刊名 | CANADIAN JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2018-10-01 |
| 卷号 | 96期号:10页码:939-948 |
| 关键词 | N-chloramine antibacterial agents organic synthesis perfluorophenyl azide chemistry polyurethane surface modification |
| ISSN号 | 0008-4042 |
| DOI | 10.1139/cjc-2018-0156 |
| 通讯作者 | Li, Lingdong(lild@dlut.edu.cn) |
| 英文摘要 | To control the pathogen cross contaminations on medical material surface, there is a pressing need to develop antimicrobial materials with highly efficacious surface biocidal activity. In this work, N-chloramine precursors containing a quaternary ammonium unit and perfluorophenyl azide unit were synthesized and covalently immobilized on inert polyurethane (PU) film upon UV light irradiation. The surface modification was confirmed by contact angle, Fourier transform infrared (ATR FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS), and atomic force microscopy (AFM) analyses. After bleaching treatment, satisfactory biocidal activity was achieved for the surface-modified PU films. It was found that the introduced surface QA center contributed an even faster surface contact killing behavior and that precursors with a longer structural linker caused higher surface chlorine content and higher antimicrobial efficacy. This approach provides a novel and facile method that enables the covalent immobilization of N-chloramine precursors on inert polymeric surface to produce durable antimicrobial materials. |
| WOS关键词 | QUATERNARY AMMONIUM MOIETIES ; HALAMINE POLYMERIC BIOCIDES ; ANTIBACTERIAL ACTIVITY ; STAPHYLOCOCCUS-AUREUS ; POLY(ETHYLENE-TEREPHTHALATE) ; COTTON ; FUNCTIONALIZATION ; NANOPARTICLES ; DISINFECTION ; FABRICATION |
| 资助项目 | Fundamental Research Funds for the Central Universities[DUT14RC(3)081] ; Fundamental Research Funds for the Central Universities[DUT17LK17] ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation[21501018] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000445699400007 |
| 出版者 | CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS |
| 资助机构 | Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/166998]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Li, Lingdong |
| 作者单位 | 1.Dalian Univ Technol, Sch Food & Environm, 2 Dagong Rd, Panjin 124221, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian, Peoples R China 3.Dalian Univ Technol, State Key Lab Fine Chem, Sch Petr & Chem Engn, 2 Dagong Rd, Panjin 124221, Peoples R China 4.Changchun Univ Technol, Jilin Prov Key Lab Carbon Fiber Dev & Applicat, Coll Chem & Life Sci, Changchun 130012, Jilin, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gai, Fangyuan,Wang, Hande,Li, Lingdong,et al. Novel N-chloramine precursors for antimicrobial application: synthesis and facile covalent immobilization on polyurethane surface based on perfluorophenyl azide (PFPA) chemistry[J]. CANADIAN JOURNAL OF CHEMISTRY,2018,96(10):939-948. |
| APA | Gai, Fangyuan.,Wang, Hande.,Li, Lingdong.,Chi, Xiaofang.,Zhang, Fengxiang.,...&Zhao .(2018).Novel N-chloramine precursors for antimicrobial application: synthesis and facile covalent immobilization on polyurethane surface based on perfluorophenyl azide (PFPA) chemistry.CANADIAN JOURNAL OF CHEMISTRY,96(10),939-948. |
| MLA | Gai, Fangyuan,et al."Novel N-chloramine precursors for antimicrobial application: synthesis and facile covalent immobilization on polyurethane surface based on perfluorophenyl azide (PFPA) chemistry".CANADIAN JOURNAL OF CHEMISTRY 96.10(2018):939-948. |
入库方式： OAI收割
来源：大连化学物理研究所
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