Synthesis of Pinacol Arylboronates from Aromatic Amines: A Metal-Free Transformation
文献类型：期刊论文
| 作者 | Wang, Jianbo; Qiu, Di; Jin, Liang; Zheng, Zhitong; Meng, He; Mo, Fanyang; Wang, Xi; Zhang, Yan |
| 刊名 | JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2013-03-01 |
| 卷号 | 78期号:5页码:1923-1933 |
| ISSN号 | 0022-3263 |
| DOI | 10.1021/jo3018878 |
| 文献子类 | Article |
| 英文摘要 | A metal-free borylation process based on Sandmeyer-type transformation using arylamines derivatives as the substrates has been developed. Through optimization of the reaction conditions, this novel conversion can be successfully applied to a wide range of aromatic amines, affording borylation products in moderate to good yields. Various functionalized arylboronates, which are difficult to access by other methods, can be easily obtained with this metal free transformation. Moreover, this transformation can be followed by Suzuki-Miyaura cross coupling without purification of the borylation products, which enhances the practical usefulness of this method. A possible reaction mechanism involving radical species has been proposed. |
| WOS关键词 | PALLADIUM-CATALYZED BORYLATION ; CROSS-COUPLING REACTION ; C-H BONDS ; ELECTROPHILIC ARENE BORYLATION ; ARYL HALIDES ; ORGANOBORON COMPOUNDS ; ORGANIC-SYNTHESIS ; ROOM-TEMPERATURE ; DIRECT CONVERSION ; ALKYL NITRITES |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000315707500027 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/167230]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Mo, Fanyang |
| 作者单位 | Peking Univ, Coll Chem, Key Lab Bioorgan Chem & Mol Engn, Beijing Natl Lab Mol Sci,Minist Educ, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Jianbo,Qiu, Di,Jin, Liang,et al. Synthesis of Pinacol Arylboronates from Aromatic Amines: A Metal-Free Transformation[J]. JOURNAL OF ORGANIC CHEMISTRY,2013,78(5):1923-1933. |
| APA | Wang, Jianbo.,Qiu, Di.,Jin, Liang.,Zheng, Zhitong.,Meng, He.,...&Zhang, Yan.(2013).Synthesis of Pinacol Arylboronates from Aromatic Amines: A Metal-Free Transformation.JOURNAL OF ORGANIC CHEMISTRY,78(5),1923-1933. |
| MLA | Wang, Jianbo,et al."Synthesis of Pinacol Arylboronates from Aromatic Amines: A Metal-Free Transformation".JOURNAL OF ORGANIC CHEMISTRY 78.5(2013):1923-1933. |
入库方式： OAI收割
来源：大连化学物理研究所
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