Ambient Mass Spectrometry Imaging: Plasma Assisted Laser Desorption Ionization Mass Spectrometry Imaging and Its Applications
文献类型：期刊论文
| 作者 | Tang, Fei3; Feng, Baosheng2; Zhang, Jialing2; Chang, Cuilan2; Li, Liping2; Li, Min2; Xiong, Xingchuang1; Guo, Chengan3; Bai, Yu2; Liu, Huwei2 |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2014-05-06 |
| 卷号 | 86期号:9页码:4164-4169 |
| ISSN号 | 0003-2700 |
| DOI | 10.1021/ac403310k |
| 文献子类 | Article |
| 英文摘要 | Mass spectrometry imaging (MSI) has been widely used in many research areas for the advantages of providing informative molecular distribution with high specificity. Among the recent progress, ambient MSI has attracted increasing interests owing to its characteristics of ambient, in situ, and nonpretreatment analysis. Here, we are presenting the ambient MSI for traditional Chinese medicines (TCMs) and authentication of work of art and documents using plasma assisted laser desorption ionization mass spectrometry (PALDI-MS). Compared with current ambient MSI methods, an excellent average resolution of 60 mu m x 60 mu m pixel size was achieved using this system. The feasibility of PALDI-based MSI was confirmed by seal imaging, and its authentication applications were demonstrated by imaging of printed Chinese characters. Imaging of the Radix Scutellariae slice showed that the two active components, baicalein and wogonin, mainly were distributed in the epidermis of the root, which proposed an approach for distinguishing TCMs' origins and the distribution of active components of TCMs and exploring the environmental effects of plant growth. PALDI-MS imaging provides a strong complement for the MSI strategy with the enhanced spatial resolution, which is promising in many research fields, such as artwork identification, TCMs' and botanic research, pharmaceutical applications, etc. |
| WOS关键词 | ELECTROSPRAY-IONIZATION ; ATMOSPHERIC-PRESSURE ; SCUTELLARIAE-RADIX ; BAICALEIN ; WOGONIN ; CANCER ; TISSUE ; LOCALIZATION ; METABOLITES ; MICROSCOPE |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000335719900017 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/167338]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Bai, Yu |
| 作者单位 | 1.Natl Inst Metrol, Beijing 100013, Peoples R China 2.Peking Univ, Key Lab Bioorgan Chem & Mol Engn, Beijing Natl Lab Mol Sci, Minist Educ,Inst Analyt Chem,Coll Chem & Mol Engn, Beijing 100871, Peoples R China 3.Tsinghua Univ, Dept Precis Instrument, State Key Lab Precis Measurement Technol & Instru, Beijing 100084, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tang, Fei,Feng, Baosheng,Zhang, Jialing,et al. Ambient Mass Spectrometry Imaging: Plasma Assisted Laser Desorption Ionization Mass Spectrometry Imaging and Its Applications[J]. ANALYTICAL CHEMISTRY,2014,86(9):4164-4169. |
| APA | Tang, Fei.,Feng, Baosheng.,Zhang, Jialing.,Chang, Cuilan.,Li, Liping.,...&Liu, Huwei.(2014).Ambient Mass Spectrometry Imaging: Plasma Assisted Laser Desorption Ionization Mass Spectrometry Imaging and Its Applications.ANALYTICAL CHEMISTRY,86(9),4164-4169. |
| MLA | Tang, Fei,et al."Ambient Mass Spectrometry Imaging: Plasma Assisted Laser Desorption Ionization Mass Spectrometry Imaging and Its Applications".ANALYTICAL CHEMISTRY 86.9(2014):4164-4169. |
入库方式： OAI收割
来源：大连化学物理研究所
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