Conversion of Aromatic Amino into Trifluoromethyl Groups through a Sandmeyer-Type Transformation
文献类型：期刊论文
| 作者 | Zhang, Yan; Wang, Xi; Xu, Yan; Zhou, Yujing; Wang, Jianbo |
| 刊名 | SYNTHESIS-STUTTGART
 |
| 出版日期 | 2014-08-01 |
| 卷号 | 46期号:16页码:2143-2148 |
| 关键词 | Trifluoromethylation Aromatic Amines Diazonium Salts Silver Sandmeyer Reaction |
| ISSN号 | 0039-7881 |
| DOI | 10.1055/s-0033-1338659 |
| 文献子类 | Article |
| 英文摘要 | A novel strategy for aromatic trifluoromethylation by converting amino into trifluoromethyl groups via a Sandmeyer-type reaction is reported. The transformation involves diazotization of the aromatic amines with tert-butyl nitrite and hydrochloric acid to form aryldiazonium chlorides, followed by trifluoromethylation with trifluoromethylsilver at low temperature. Various readily available aromatic amines are smoothly converted under mild conditions. |
| WOS关键词 | PALLADIUM-CATALYZED TRIFLUOROMETHYLATION ; SILVER-MEDIATED TRIFLUOROMETHYLATION ; BORONIC ACIDS ; ARYLBORONIC ACIDS ; SYNTHETIC METHODS ; DIAZONIUM SALTS ; ALKYL NITRITES ; ARYL STANNANES ; ARENES ; PERFLUOROALKYLATION |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000340875300004 |
| 出版者 | GEORG THIEME VERLAG KG |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/167358]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Wang, Jianbo |
| 作者单位 | Peking Univ, Coll Chem, Key Lab Bioorgan Chem & Mol Engn, Beijing Natl Lab Mol Sci BNLMS,Minist Educ, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Yan,Wang, Xi,Xu, Yan,et al. Conversion of Aromatic Amino into Trifluoromethyl Groups through a Sandmeyer-Type Transformation[J]. SYNTHESIS-STUTTGART,2014,46(16):2143-2148. |
| APA | Zhang, Yan,Wang, Xi,Xu, Yan,Zhou, Yujing,&Wang, Jianbo.(2014).Conversion of Aromatic Amino into Trifluoromethyl Groups through a Sandmeyer-Type Transformation.SYNTHESIS-STUTTGART,46(16),2143-2148. |
| MLA | Zhang, Yan,et al."Conversion of Aromatic Amino into Trifluoromethyl Groups through a Sandmeyer-Type Transformation".SYNTHESIS-STUTTGART 46.16(2014):2143-2148. |
入库方式： OAI收割
来源：大连化学物理研究所
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