Total Syntheses of (-)-Huperzine Q and (+)-Lycopladines B and C
文献类型：期刊论文
| 作者 | Wu, Jinbao1,2; Hong, Benke1,2; Lei, Xiaoguang1,3,4; Li, Houhua1; Zhang, Jing1,2 |
| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2015-01-12 |
| 卷号 | 54期号:3页码:1011-1015 |
| 关键词 | Alkaloids Epoxyamines Metathesis Natural Products Total Synthesis |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.201409503 |
| 文献子类 | Article |
| 英文摘要 | Utilizing a late-stage enamine bromofunctionalization strategy, the twelve-step total synthesis of (-)-huperzine Q was accomplished. Furthermore, the first total syntheses of (+)-lycopladines B and C are described. An unprecedented X-ray crystal structure of an unusual epoxyamine intermediate is also reported, and the synthetic application of this intermediate in natural product synthesis is demonstrated. |
| WOS关键词 | LYCOPODIUM ALKALOIDS ; CARBONYL OLEFINATION ; FUNCTIONAL-GROUP ; RECENT PROGRESS ; ENOL ETHERS ; ALKENES ; EPOXYAMINES ; REAGENTS ; FAWCETTIMINE ; METATHESIS |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000348372200053 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/167364]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Lei, Xiaoguang |
| 作者单位 | 1.NIBS, Beijing 102206, Peoples R China 2.Tianjin Univ, Sch Pharmaceut Sci & Technol, Tianjin 300072, Peoples R China 3.Peking Univ, Beijing Natl Lab Mol Sci, Key Lab Bioorgan Chem & Mol Engn, Minist Educ,Dept Chem Biol,Coll Chem & Mol Engn,S, Beijing 100871, Peoples R China 4.Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Jinbao,Hong, Benke,Lei, Xiaoguang,et al. Total Syntheses of (-)-Huperzine Q and (+)-Lycopladines B and C[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2015,54(3):1011-1015. |
| APA | Wu, Jinbao,Hong, Benke,Lei, Xiaoguang,Li, Houhua,&Zhang, Jing.(2015).Total Syntheses of (-)-Huperzine Q and (+)-Lycopladines B and C.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,54(3),1011-1015. |
| MLA | Wu, Jinbao,et al."Total Syntheses of (-)-Huperzine Q and (+)-Lycopladines B and C".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 54.3(2015):1011-1015. |
入库方式： OAI收割
来源：大连化学物理研究所
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