Live-cell bioorthogonal Raman imaging
文献类型：期刊论文
| 作者 | Chen, Xing1; Hong, Senlian; Lin, Liang; Xiao, Min |
| 刊名 | CURRENT OPINION IN CHEMICAL BIOLOGY
 |
| 出版日期 | 2015-02-01 |
| 卷号 | 24页码:91-96 |
| ISSN号 | 1367-5931 |
| DOI | 10.1016/j.cbpa.2014.10.018 |
| 文献子类 | Review |
| 英文摘要 | Live-cell microscopy demands high specificity, sensitivity, and minimal perturbation to the biomolecules of interest. Meeting all these criteria has been challenging in cellular imaging. Toward this goal, a bioorthogonal Raman imaging method has recently emerged by exploiting small Raman reporters that possess Raman signals that do not overlap with the naturally existing biomolecules in the cells. The Raman reporters are metabolically incorporated into the target biomolecules for direct visualization. Herein, we review recent advances in the methodological development and the proof-of-concept applications of the live-cell bioorthogonal Raman imaging technique. |
| WOS关键词 | NEWLY SYNTHESIZED PROTEINS ; SCATTERING MICROSCOPY ; FLUORESCENCE MICROSCOPY ; CHEMICAL REPORTERS ; SRS MICROSCOPY ; BIOMOLECULES ; VISUALIZATION ; SPECTROSCOPY ; EDU |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biophysics |
| 语种 | 英语 |
| WOS记录号 | WOS:000349574700011 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/167366]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Chen, Xing |
| 作者单位 | 1.Peking Univ, Beijing Natl Lab Mol Sci, Key Lab Bioorgan Chem & Mol Engn, Minist Educ,Coll Chem & Mol Engn,Synthet & Funct, Beijing 100871, Peoples R China 2.Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Xing,Hong, Senlian,Lin, Liang,et al. Live-cell bioorthogonal Raman imaging[J]. CURRENT OPINION IN CHEMICAL BIOLOGY,2015,24:91-96. |
| APA | Chen, Xing,Hong, Senlian,Lin, Liang,&Xiao, Min.(2015).Live-cell bioorthogonal Raman imaging.CURRENT OPINION IN CHEMICAL BIOLOGY,24,91-96. |
| MLA | Chen, Xing,et al."Live-cell bioorthogonal Raman imaging".CURRENT OPINION IN CHEMICAL BIOLOGY 24(2015):91-96. |
入库方式： OAI收割
来源：大连化学物理研究所
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