Calcium deficiency in hydroxyapatite and its drug delivery applications
文献类型：期刊论文
| 作者 | Rajagopalan, Vijayaraghavan1; Koppala, Sivasankar1,2; Swamiappan, Sasikumar1; Gangarajula, Yuvaraj3; Xu, Lei1; Sadasivuni, Kishor Kumar4; Ponnamma, Deepalekshmi5 |
| 刊名 | MICRO & NANO LETTERS
 |
| 出版日期 | 2018-04-01 |
| 卷号 | 13期号:4页码:562-564 |
| 关键词 | Calcium Compounds Bioceramics Drug Delivery Systems Drugs Nanoparticles Particle Size Nanofabrication Nanomedicine Fourier Transform Infrared Spectra Precipitation Calcination X-ray Diffraction Scanning Electron Microscopy X-ray Chemical Analysis Nanoporous Materials Porosity Drug Delivery Applications Calcium Deficient Hydroxyapatites Precipitation Method Calcined Samples Fourier Transformation Infrared Spectroscopy Powder X-ray Diffraction Scanning Electron Microscopy Energy-dispersive X-ray Spectroscopy Phase Purity Particle Size Particle Shape Hap Structure Ciprofloxacin Sustained Drug Release Phosphate Buffer Solution Porous Structure [Ca10-x(Po4)(6)(Oh)(2)] |
| ISSN号 | 1750-0443 |
| DOI | 10.1049/mnl.2016.0675 |
| 文献子类 | Article |
| 英文摘要 | In this work, calcium deficient hydroxyapatites (HAPs) [Ca10-x(PO4)(6)(OH)(2)] [where x = 0 - 0.3] were synthesised by precipitation method and calcined samples were characterised by Fourier transformation infrared spectroscopy, powder X-ray diffraction, scanning electron microscopy and energy-dispersive X-ray spectroscopy techniques to check phase purity, calcium deficiency, particle size and shape. The results indicate that the structure of the HAP can tolerate a calcium deficiency up to 0.2. The calcium deficient HAP (x = 0.1) powder was found to be highly porous with a particle size below 200 nm. This powder was used as a drug delivery carrier for the drug, ciprofloxacin and sustained release of the drug in the phosphate buffer solution was investigated. |
| WOS关键词 | ADSORPTION |
| WOS研究方向 | Science & Technology - Other Topics ; Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000429200100032 |
| 出版者 | INST ENGINEERING TECHNOLOGY-IET |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/169004]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Rajagopalan, Vijayaraghavan |
| 作者单位 | 1.Kunming Univ Sci & Technol, Fac Met & Energy Engn, Kunming 650093, Yunnan, Peoples R China 2.VIT Univ, Sch Adv Sci, Dept Chem, Vellore 632014, Tamil Nadu, India 3.Chinese Acad Sci, Dalian Inst Chem Phys, Mossbauer Effect Data Ctr, Dalian 116023, Peoples R China 4.Qatar Univ, Dept Mech & Ind Engn, POB 2713, Doha, Qatar 5.Qatar Univ, Ctr Adv Mat, POB 2713, Doha, Qatar |
| 推荐引用方式 GB/T 7714 | Rajagopalan, Vijayaraghavan,Koppala, Sivasankar,Swamiappan, Sasikumar,et al. Calcium deficiency in hydroxyapatite and its drug delivery applications[J]. MICRO & NANO LETTERS,2018,13(4):562-564. |
| APA | Rajagopalan, Vijayaraghavan.,Koppala, Sivasankar.,Swamiappan, Sasikumar.,Gangarajula, Yuvaraj.,Xu, Lei.,...&Ponnamma, Deepalekshmi.(2018).Calcium deficiency in hydroxyapatite and its drug delivery applications.MICRO & NANO LETTERS,13(4),562-564. |
| MLA | Rajagopalan, Vijayaraghavan,et al."Calcium deficiency in hydroxyapatite and its drug delivery applications".MICRO & NANO LETTERS 13.4(2018):562-564. |
入库方式： OAI收割
来源：大连化学物理研究所
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