Detection of Amino Acids and Polypeptides by Electrospray Ionization-Ion Mobility Spectrometry
文献类型：期刊论文
| 作者 | Chen Chuang2; Li Hai-Yang2; Kong Jing-Lin1; Liu Wei-Wei1; Ding Jun-Jie1; Zhang Lin1; Li Bao-Qiang1; Qin Mo-Lin1 |
| 刊名 | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2017-11-01 |
| 卷号 | 45期号:11页码:1583-1588 |
| 关键词 | Electrospray Ion Mobility Spectrometry Amino Acid Polypeptide Reduced Mobility |
| ISSN号 | 0253-3820 |
| DOI | 10.11895/j.issn.0253.3820.171052 |
| 文献子类 | Article |
| 英文摘要 | The electrospray ionization. ion mobility spectrometric (ESI-IMS) technique has the potential as an analytical separation tool in analyzing polypeptides and amino acids for fast screening unknown samples in anti-chemical and biological terror attacks. A method for detecting several polypeptides and amino acids was developed based on ESI-IMS using air as drift gas at room temperature. The ion mobility of four amino acids and two polypeptides dissolved in methanol was determined on the system at elution rate of 2 mu L/min. The spectra of these compounds had characteristics of finger-printing maps. The limit of detection of this instrument for Substance P could reach 855 ng/mL in 1 min. The results showed that a small, self-contained ESI-IMS instrument with reservoirs of air could be used to quickly detect and accurately identify polypeptides and amino acids. |
| WOS关键词 | PERFORMANCE ; SEPARATION ; ISOMERS |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000419177900001 |
| 出版者 | ELSEVIER SCIENCE INC |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/169212]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Kong Jing-Lin |
| 作者单位 | 1.Inst Chem Def, Beijing 102205, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen Chuang,Li Hai-Yang,Kong Jing-Lin,et al. Detection of Amino Acids and Polypeptides by Electrospray Ionization-Ion Mobility Spectrometry[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2017,45(11):1583-1588. |
| APA | Chen Chuang.,Li Hai-Yang.,Kong Jing-Lin.,Liu Wei-Wei.,Ding Jun-Jie.,...&Qin Mo-Lin.(2017).Detection of Amino Acids and Polypeptides by Electrospray Ionization-Ion Mobility Spectrometry.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,45(11),1583-1588. |
| MLA | Chen Chuang,et al."Detection of Amino Acids and Polypeptides by Electrospray Ionization-Ion Mobility Spectrometry".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 45.11(2017):1583-1588. |
入库方式： OAI收割
来源：大连化学物理研究所
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