Mercaptophenylboronic acid-capped Mn-doped ZnS quantum dots for highly selective and sensitive fluorescence detection of glycoproteins
文献类型：期刊论文
| 作者 | He, Xiwen1; Zhang, Yukui1,3; Chang, Lifang1; Chen, Langxing1,2 |
| 刊名 | SENSORS AND ACTUATORS B-CHEMICAL
 |
| 出版日期 | 2017-05-01 |
| 卷号 | 243页码:72-77 |
| 关键词 | Mn-doped Zns Quantum Dots Fluorescent Enhanced Sensor Boronate-affinity Glycoproteins Transferrin |
| ISSN号 | 0925-4005 |
| DOI | 10.1016/j.snb.2016.11.121 |
| 文献子类 | Article |
| 英文摘要 | In this work, a novel fluorescent turn-on sensor for the detection of glycoproteins based upon measuring the fluorescence enhancement of mercaptophenylboronic acid-capped Mn-doped ZnS quantum dots (QDs@MBA) was developed. Transferrin (TRF), as one of glycoproteins, was introduced to evaluate characteristics of the fluorescent probe. The TRF bound onto MBA via boronate affinity interaction can efficiently enhance the fluorescence of QDs@MBA through a blocked electron transfer process from the QDs to the boronic acid moieties. Approximately 2.6-fold fluorescence enhancement of Qps@MBA at 610 nm can be observed in presence of 10.0 mu M TRF within 10 min. The QDs@MBA can sensitively detect down to 5.69 x 10(-9) M TRF in aqueous solution and the linear range is 0.10-10.0 mu M. Moreover, QPs@MBA was also applied to detect TRF in serum sample, and the recovery can achieve 87.9%-96.5%. This sensor shows a great potential for detecting glyproteins present in the complex biological or biomedical samples. (C) 2016 Elsevier B.V. All rights reserved. |
| WOS关键词 | ROOM-TEMPERATURE PHOSPHORESCENCE ; ENERGY-TRANSFER ; PROTEIN GLYCOSYLATION ; BORONIC ACIDS ; IN-VITRO ; SENSOR ; NANOPARTICLES ; NANOCRYSTALS ; EMISSION ; AFFINITY |
| WOS研究方向 | Chemistry ; Electrochemistry ; Instruments & Instrumentation |
| 语种 | 英语 |
| WOS记录号 | WOS:000395969100011 |
| 出版者 | ELSEVIER SCIENCE SA |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/169316]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Chen, Langxing |
| 作者单位 | 1.Nankai Univ, Coll Chem, Res Ctr Analyt Sci, Tianjin Key Lab Biosensing & Mol Recognit,State K, Tianjin 300071, Peoples R China 2.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Xiwen,Zhang, Yukui,Chang, Lifang,et al. Mercaptophenylboronic acid-capped Mn-doped ZnS quantum dots for highly selective and sensitive fluorescence detection of glycoproteins[J]. SENSORS AND ACTUATORS B-CHEMICAL,2017,243:72-77. |
| APA | He, Xiwen,Zhang, Yukui,Chang, Lifang,&Chen, Langxing.(2017).Mercaptophenylboronic acid-capped Mn-doped ZnS quantum dots for highly selective and sensitive fluorescence detection of glycoproteins.SENSORS AND ACTUATORS B-CHEMICAL,243,72-77. |
| MLA | He, Xiwen,et al."Mercaptophenylboronic acid-capped Mn-doped ZnS quantum dots for highly selective and sensitive fluorescence detection of glycoproteins".SENSORS AND ACTUATORS B-CHEMICAL 243(2017):72-77. |
入库方式： OAI收割
来源：大连化学物理研究所
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