Synthesis of quaternary phosphonium N-chloramine biocides for antimicrobial applications
文献类型：期刊论文
| 作者 | Zhang, Fengxiang1; Li, Lingdong1; Zhou, Hao2; Gai, Fangyuan1; Chi, Xiaofang1; Zhao, Yuebiao1; Zhao (Kent), Zongbao3 |
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:22页码:13244-13249 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c6ra24954j |
| 文献子类 | Article |
| 英文摘要 | The recently developed quaternary ammonium (QA) N-chloramine has been proved to be a promising "composite" biocide with drastically boosted antibacterial efficacy afforded by the QA moiety. In this work, a series of quaternary phosphonium (QP) N-chloramine biocides, covalently combining an N-chloramine moiety and a QP moiety via varied aliphatic methylene units, were synthesized by means of multi-step chemical reactions. Preliminary antibacterial tests against both Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) showed that the synthetic QP N-chloramine exhibited distinctively higher biocidal efficacy than the QA counterpart. Furthermore, bactericidal tests also indicated that QP N-chloramine with a linker of -(CH2)(12)-showed the highest biocidal efficacy, suggesting synergistic action between the N-chloramine moiety and QP moiety. |
| WOS关键词 | HALAMINE POLYMERIC BIOCIDES ; AMMONIUM MOIETIES ; BACTERIA ; CELLULOSE ; DISINFECTANTS ; NANOPARTICLES ; ELUCIDATION ; MECHANISMS ; FABRICS ; SALT |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000395935300027 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/169514]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Li, Lingdong |
| 作者单位 | 1.Dalian Univ Technol, State Key Lab Fine Chem, Sch Chem & Petr Engn, 2 Dagong Rd, Liaodongwan New Dist 124221, Panjin, Peoples R China 2.Dalian Univ Technol, Sch Food & Environm, 2 Dagong Rd, Liaodongwan New Dist 124221, Panjin, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Fengxiang,Li, Lingdong,Zhou, Hao,et al. Synthesis of quaternary phosphonium N-chloramine biocides for antimicrobial applications[J]. RSC ADVANCES,2017,7(22):13244-13249. |
| APA | Zhang, Fengxiang.,Li, Lingdong.,Zhou, Hao.,Gai, Fangyuan.,Chi, Xiaofang.,...&Zhao .(2017).Synthesis of quaternary phosphonium N-chloramine biocides for antimicrobial applications.RSC ADVANCES,7(22),13244-13249. |
| MLA | Zhang, Fengxiang,et al."Synthesis of quaternary phosphonium N-chloramine biocides for antimicrobial applications".RSC ADVANCES 7.22(2017):13244-13249. |
入库方式： OAI收割
来源：大连化学物理研究所
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