Radical-Mediated 1,2-Formyl/Carbonyl Functionalization of Alkenes and Application to the Construction of Medium-Sized Rings
文献类型：期刊论文
| 作者 | Li, Xiao-Hua1; Wang, Na1; Yang, Ning-Yuan1; Liu, Xin-Yuan1; Li, Zhong-Liang1,2 |
| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2016-11-21 |
| 卷号 | 55期号:48页码:15100-15104 |
| 关键词 | Alkenes Heterocycles Medium-ring Systems Radicals Synthetic Methods |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.201608198 |
| 文献子类 | Article |
| 英文摘要 | A novel radical 1,2-formylfunctionalization of alkenes involving 1,2(4,5)-formyl migration triggered by addition of various carbon- and heteroatom-centered radicals to alkenes has been developed for the first time, thus providing straightforward access to diverse beta-functionalized aldehydes with good efficiency, remarkable selectivity, and excellent functional group tolerance. Analogous transformations mediated by a keto-carbonyl migration have also been effected under similar conditions. This method was used to access ring systems including various benzannulated nine-, ten-, and eleven-membered rings, complex 6-5(6,7)-6(5) fused rings, and bridged rings with diverse functionalities. |
| WOS关键词 | LIGHT PHOTOREDOX CATALYSIS ; HYDROGEN-ATOM TRANSFER ; C-H FUNCTIONALIZATION ; ORGANIC-SYNTHESIS ; CARBON RADICALS ; TRIFLUOROMETHYLTHIOLATION REACTIONS ; OXIDATIVE TRIFLUOROMETHYLATION ; FRAGMENTATION REACTIONS ; BETA-FRAGMENTATION ; CYCLIZATION |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000388258000038 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/169762]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Liu, Xin-Yuan |
| 作者单位 | 1.South Univ Sci & Technol China, Dept Chem, Shenzhen 518055, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Xiao-Hua,Wang, Na,Yang, Ning-Yuan,et al. Radical-Mediated 1,2-Formyl/Carbonyl Functionalization of Alkenes and Application to the Construction of Medium-Sized Rings[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2016,55(48):15100-15104. |
| APA | Li, Xiao-Hua,Wang, Na,Yang, Ning-Yuan,Liu, Xin-Yuan,&Li, Zhong-Liang.(2016).Radical-Mediated 1,2-Formyl/Carbonyl Functionalization of Alkenes and Application to the Construction of Medium-Sized Rings.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,55(48),15100-15104. |
| MLA | Li, Xiao-Hua,et al."Radical-Mediated 1,2-Formyl/Carbonyl Functionalization of Alkenes and Application to the Construction of Medium-Sized Rings".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 55.48(2016):15100-15104. |
入库方式： OAI收割
来源：大连化学物理研究所
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