Ruthenium(II)-Catalyzed C-H Activation of Imidamides and Divergent Couplings with Diazo Compounds: Substrate-Controlled Synthesis of Indoles and 3H-Indoles
文献类型：期刊论文
| 作者 | Qi, Zisong2; Li, Xingwei2; Yang, Xifa1,2; Li, Yunyun1,2; Wang, He2 |
| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2016-09-19 |
| 卷号 | 55期号:39页码:11877-11881 |
| 关键词 | C-h Activation Diazo Compounds Indoles Ruthenium Transition-metal Catalysis |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.201606316 |
| 文献子类 | Article |
| 英文摘要 | Indoles are an important structural motif that is commonly found in biologically active molecules. In this work, conditions for divergent couplings between imidamides and acceptor-acceptor diazo compounds were developed that afforded NH indoles and 3H-indoles under ruthenium catalysis. The coupling of alpha-diazoketoesters afforded NHindoles by cleavage of the C(N2)-C(acyl) bond whereas alpha-diazomalonates gave 3H-indoles by C-N bond cleavage. This reaction constitutes the first intermolecular coupling of diazo substrates with arenes by ruthenium-catalyzed C-H activation. |
| WOS关键词 | RH(III)-CATALYZED SYNTHESIS ; ONE-POT ; BOND FUNCTIONALIZATIONS ; ALPHA-DIAZOACETAMIDES ; CATALYZED REACTIONS ; ROOM-TEMPERATURE ; DIRECTING GROUPS ; FUSED INDOLES ; N-OXIDES ; CYCLIZATION |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000384713100029 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/169892]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Li, Xingwei |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qi, Zisong,Li, Xingwei,Yang, Xifa,et al. Ruthenium(II)-Catalyzed C-H Activation of Imidamides and Divergent Couplings with Diazo Compounds: Substrate-Controlled Synthesis of Indoles and 3H-Indoles[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2016,55(39):11877-11881. |
| APA | Qi, Zisong,Li, Xingwei,Yang, Xifa,Li, Yunyun,&Wang, He.(2016).Ruthenium(II)-Catalyzed C-H Activation of Imidamides and Divergent Couplings with Diazo Compounds: Substrate-Controlled Synthesis of Indoles and 3H-Indoles.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,55(39),11877-11881. |
| MLA | Qi, Zisong,et al."Ruthenium(II)-Catalyzed C-H Activation of Imidamides and Divergent Couplings with Diazo Compounds: Substrate-Controlled Synthesis of Indoles and 3H-Indoles".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 55.39(2016):11877-11881. |
入库方式： OAI收割
来源：大连化学物理研究所
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