An Expedient Method for Regioselective Methylation of Catechol Coumarins
文献类型：期刊论文
| 作者 | Ge Guangbo3; Lu Junxia1,3; Wang Ping3; Hou Jie4; Zou Liwei3; Cui Pan3; Yang Ling3; Gong Xiaojie2 |
| 刊名 | CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
 |
| 出版日期 | 2016-10-01 |
| 卷号 | 32期号:5页码:786-791 |
| 关键词 | Catechol Coumarin Regioselective Methylation Density Functional Theory |
| ISSN号 | 1005-9040 |
| DOI | 10.1007/s40242-016-6147-x |
| 文献子类 | Article |
| 英文摘要 | An expedient and efficient method for selective methylation of catechol coumarins by working with different alkalis under appropriate reaction conditions was reported. Esculetins were selectively methylated at position 6 and position 7 in good yields using CH3I in the presence of NaH and Na2CO3, respectively. However, daphnetins showed less regioselectivity under the same reaction conditions. Furthermore, the site preference for the methylation reaction was interpreted by the density functional theory at B3LYP/6-31+G(d) level. |
| WOS关键词 | ERYCIBE-OBTUSIFOLIA BENTH ; ANTITUMOR-ACTIVITY ; CELL-LINE ; IN-VITRO ; SCOPOLETIN ; ANGIOGENESIS ; DERIVATIVES |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000386542500014 |
| 出版者 | HIGHER EDUCATION PRESS |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/169968]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Ge Guangbo; Gong Xiaojie |
| 作者单位 | 1.Dalian Univ, Coll Environm & Chem Engn, Dalian 116622, Peoples R China 2.Dalian Univ, Coll Med, Dalian 116622, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian 116023, Peoples R China 4.Dalian Med Univ, Coll Basic Med Sci, Dalian 116044, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ge Guangbo,Lu Junxia,Wang Ping,et al. An Expedient Method for Regioselective Methylation of Catechol Coumarins[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2016,32(5):786-791. |
| APA | Ge Guangbo.,Lu Junxia.,Wang Ping.,Hou Jie.,Zou Liwei.,...&Gong Xiaojie.(2016).An Expedient Method for Regioselective Methylation of Catechol Coumarins.CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,32(5),786-791. |
| MLA | Ge Guangbo,et al."An Expedient Method for Regioselective Methylation of Catechol Coumarins".CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 32.5(2016):786-791. |
入库方式： OAI收割
来源：大连化学物理研究所
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