A crucial role for spatial distribution in bacterial quorum sensing
文献类型：期刊论文
| 作者 | Lou, Ruyun1,2; Gao, Meng1,2; Zheng, Huizhen1,2; Ren, Ying1,2; Wu, Fan1,2; Yu, Weiting1; Liu, Xiudong3; Ma, Xiaojun1 |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2016-10-04 |
| 卷号 | 6 |
| ISSN号 | 2045-2322 |
| DOI | 10.1038/srep34695 |
| 文献子类 | Article |
| 英文摘要 | Quorum sensing (QS) is a process that enables bacteria to communicate using secreted signaling molecules, and then makes a population of bacteria to regulate gene expression collectively and control behavior on a community-wide scale. Theoretical studies of efficiency sensing have suggested that both mass-transfer performance in the local environment and the spatial distribution of cells are key factors affecting QS. Here, an experimental model based on hydrogel microcapsules with a three-dimensional structure was established to investigate the influence of the spatial distribution of cells on bacterial QS. Vibrio harveyi cells formed different spatial distributions in the microcapsules, i.e., they formed cell aggregates with different structures and sizes. The cell aggregates displayed stronger QS than did unaggregated cells even when equal numbers of cells were present. Large aggregates (LA) of cells, with a size of approximately 25 mu m, restricted many more autoinducers (AIs) than did small aggregates (SA), with a size of approximately 10 mu m, thus demonstrating that aggregate size significantly affects QS. These findings provide a powerful demonstration of the fact that the spatial distribution of cells plays a crucial role in bacterial QS. |
| WOS关键词 | ESCHERICHIA-COLI ; VIBRIO-HARVEYI ; CELL MICROENCAPSULATION ; BIOFILM FORMATION ; MICROCAPSULES ; DIFFUSION ; ALGINATE ; COMMUNICATION ; AGGREGATION ; EXPRESSION |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000384711300002 |
| 出版者 | NATURE PUBLISHING GROUP |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/169998]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Yu, Weiting; Liu, Xiudong |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Dalian Univ, Coll Environm & Chem Engn, Dalian Econ Technol Dev Zone, Dalian 116622, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lou, Ruyun,Gao, Meng,Zheng, Huizhen,et al. A crucial role for spatial distribution in bacterial quorum sensing[J]. SCIENTIFIC REPORTS,2016,6. |
| APA | Lou, Ruyun.,Gao, Meng.,Zheng, Huizhen.,Ren, Ying.,Wu, Fan.,...&Ma, Xiaojun.(2016).A crucial role for spatial distribution in bacterial quorum sensing.SCIENTIFIC REPORTS,6. |
| MLA | Lou, Ruyun,et al."A crucial role for spatial distribution in bacterial quorum sensing".SCIENTIFIC REPORTS 6(2016). |
入库方式： OAI收割
来源：大连化学物理研究所
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