One-Pot Approach to Prepare Organo-silica Hybrid Capillary Monolithic Column with Intact Mesoporous Silica Nanoparticle as Building Block
文献类型：期刊论文
| 作者 | Wu, Ren'an1; Liu, Shengju1,2; Peng, Jiaxi1,2; Liu, Zheyi1,2; Liu, Zhongshan1,2; Zhang, Hongyan1,2 |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2016-10-04 |
| 卷号 | 6 |
| ISSN号 | 2045-2322 |
| DOI | 10.1038/srep34718 |
| 文献子类 | Article |
| 英文摘要 | A facile "one-pot" approach to prepare organo-silica hybrid capillary monolithic column with intact mesoporous silica nanoparticle (IMSN) as crosslinker and building block was described. An IMSN crosslinked octadecyl-silica hybrid capillary monolithic column (IMSN-C18 monolithic column) was successfully prepared, and the effects of fabrication conditions (e.g. concentration of intact mesoporous silica nanoparticle, polycondensation temperature, content of vinyltrimethoxysilane and stearyl methacrylate) on the structures of the IMSN-C18 monolithic column were studied in detail. The IMSN-C18 hybrid monolithic column possessed uniform morphology, good mechanical and pH stability (pH 1.1-11), which was applied to the separations of alkyl benzenes, polycyclic aromatic hydrocarbons (PAHs), as well as proteins. The minimum plate height of 10.5 mu m (corresponding to 95000 N m(-1)) for butylbenzene and high reproducibility were achieved. The analysis of tryptic digest of bovine serum albumin (BSA) was carried out on the IMSN-C18 monolithic column by cLC coupled mass spectrometry (cLC-MS/MS), with the protein sequence coverage of 87.5% for BSA, demonstrating its potential application in proteomics. |
| WOS关键词 | ENE CLICK CHEMISTRY ; POLYHEDRAL OLIGOMERIC SILSESQUIOXANES ; PERFORMANCE LIQUID-CHROMATOGRAPHY ; STATIONARY PHASES ; HIGH-EFFICIENCY ; FACILE PREPARATION ; IONIC LIQUID ; ELECTROCHROMATOGRAPHY ; METHACRYLATE ; SEPARATION |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000384711500002 |
| 出版者 | NATURE PUBLISHING GROUP |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/170000]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Wu, Ren'an |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Ren'an,Liu, Shengju,Peng, Jiaxi,et al. One-Pot Approach to Prepare Organo-silica Hybrid Capillary Monolithic Column with Intact Mesoporous Silica Nanoparticle as Building Block[J]. SCIENTIFIC REPORTS,2016,6. |
| APA | Wu, Ren'an,Liu, Shengju,Peng, Jiaxi,Liu, Zheyi,Liu, Zhongshan,&Zhang, Hongyan.(2016).One-Pot Approach to Prepare Organo-silica Hybrid Capillary Monolithic Column with Intact Mesoporous Silica Nanoparticle as Building Block.SCIENTIFIC REPORTS,6. |
| MLA | Wu, Ren'an,et al."One-Pot Approach to Prepare Organo-silica Hybrid Capillary Monolithic Column with Intact Mesoporous Silica Nanoparticle as Building Block".SCIENTIFIC REPORTS 6(2016). |
入库方式： OAI收割
来源：大连化学物理研究所
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