Preparation of cyclodextrin-modified monolithic hybrid columns for the fast enantioseparation of hydroxy acids in capillary liquid chromatography
文献类型：期刊论文
| 作者 | Szwed, Kamila; Ou, Junjie; Huang, Guang; Lin, Hui; Liu, Zhongshan; Wang, Hongwei; Zou, Hanfa |
| 刊名 | JOURNAL OF SEPARATION SCIENCE
 |
| 出版日期 | 2016-03-01 |
| 卷号 | 39期号:6页码:1110-1117 |
| 关键词 | Capillary Liquid Chromatography Cyclodextrins Enantioseparation |
| ISSN号 | 1615-9306 |
| DOI | 10.1002/jssc.201501157 |
| 文献子类 | Article |
| 英文摘要 | Cyclodextrins and their derivatives are one of the most common and successful chiral selectors. However, there have been few publications about the use of cyclodextrin-modified monoliths. In this study, organic hybrid monoliths were prepared by the immobilization of derivatized -cyclodextrin alone or with l-2-allylglycine hydrochloride to the polyhedral oligomeric silsesquioxane methacryl substituted monolith. The main topic of this study is a combined system with dual chiral selectors (l-2-allylglycine hydrochloride and -cyclodextrin) as monolithic chiral stationary phase. The effect of l-2-allylglycine hydrochloride concentration on enantioseparation was investigated. The enantioseparation of the four acidic compounds with resolutions up to 2.87 was achieved within 2.5 min on the prepared chiral monolithic column in capillary liquid chromatography. Moreover, the possible mechanism of enantioseparation was discussed. |
| WOS关键词 | POLYHEDRAL OLIGOMERIC SILSESQUIOXANES ; RING-OPENING POLYMERIZATION ; ONE-POT APPROACH ; BETA-CYCLODEXTRIN ; STATIONARY PHASES ; CHIRAL SEPARATIONS ; FUNCTIONAL MONOMER ; FACILE PREPARATION ; ELECTROCHROMATOGRAPHY ; ELECTROPHORESIS |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000373617100011 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/170694]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Ou, Junjie; Zou, Hanfa |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Szwed, Kamila,Ou, Junjie,Huang, Guang,et al. Preparation of cyclodextrin-modified monolithic hybrid columns for the fast enantioseparation of hydroxy acids in capillary liquid chromatography[J]. JOURNAL OF SEPARATION SCIENCE,2016,39(6):1110-1117. |
| APA | Szwed, Kamila.,Ou, Junjie.,Huang, Guang.,Lin, Hui.,Liu, Zhongshan.,...&Zou, Hanfa.(2016).Preparation of cyclodextrin-modified monolithic hybrid columns for the fast enantioseparation of hydroxy acids in capillary liquid chromatography.JOURNAL OF SEPARATION SCIENCE,39(6),1110-1117. |
| MLA | Szwed, Kamila,et al."Preparation of cyclodextrin-modified monolithic hybrid columns for the fast enantioseparation of hydroxy acids in capillary liquid chromatography".JOURNAL OF SEPARATION SCIENCE 39.6(2016):1110-1117. |
入库方式： OAI收割
来源：大连化学物理研究所
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