Synthesis, structures, and insulin-like activity of oxidovanadium(V) complexes derived from 2-chloro-N '-(3-ethoxy-2-hydroxybenzylidene)benzohydrazide
文献类型：期刊论文
| 作者 | You, Zhonglu2; Zheng, Boyang2; Yang, Ting1; Liu, Fang2; Cheng, Xiao-Shan2 |
| 刊名 | JOURNAL OF COORDINATION CHEMISTRY
 |
| 出版日期 | 2016 |
| 卷号 | 69期号:8页码:1371-1379 |
| ISSN号 | 0095-8972 |
| 关键词 | Oxidovanadium Complex Aroylhydrazone Acetohydroxamate Maltol Insulin-like Activity |
| DOI | 10.1080/00958972.2016.1171856 |
| 文献子类 | Article |
| 英文摘要 | Three new oxidovanadium(V) complexes, [VOLL] (L = 2-chloro-N'-(3-ethoxy-2hydroxybenzylidene)benzohydrazide, L' = acetohydroxamate for 1, methylmaltolate for 2, and ethylmaltolate for 3), have been prepared. The complexes have been characterized by physicochemical methods and single-crystal X-ray determination. Vanadium in each complex is coordinated by the NOO donor set of L, the OO donor set of L', and one oxido, forming octahedral coordination. The complexes were administered intragastrically to both normal and alloxan-diabetic mice for two weeks. The biological activities show that the complexes at doses of 10.0 and 20.0mg V-kg(-1) can significantly decrease the blood glucose level in alloxan-diabetic mice, but the blood glucose level in the treated normal mice was not altered. |
| WOS关键词 | MIMETIC VANADIUM COMPLEXES ; PYLORI UREASE INHIBITION ; POLYMERIZATION CAPABILITY ; BIOLOGICAL EVALUATION ; MOLECULAR DOCKING ; IN-VITRO ; LIGANDS ; DERIVATIVES ; HYDRAZONE ; DESIGN |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | TAYLOR & FRANCIS LTD |
| WOS记录号 | WOS:000375481700007 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/170862]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | You, Zhonglu |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China 2.Liaoning Normal Univ, Dept Chem & Chem Engn, Dalian, Peoples R China |
| 推荐引用方式 GB/T 7714 | You, Zhonglu,Zheng, Boyang,Yang, Ting,et al. Synthesis, structures, and insulin-like activity of oxidovanadium(V) complexes derived from 2-chloro-N '-(3-ethoxy-2-hydroxybenzylidene)benzohydrazide[J]. JOURNAL OF COORDINATION CHEMISTRY,2016,69(8):1371-1379. |
| APA | You, Zhonglu,Zheng, Boyang,Yang, Ting,Liu, Fang,&Cheng, Xiao-Shan.(2016).Synthesis, structures, and insulin-like activity of oxidovanadium(V) complexes derived from 2-chloro-N '-(3-ethoxy-2-hydroxybenzylidene)benzohydrazide.JOURNAL OF COORDINATION CHEMISTRY,69(8),1371-1379. |
| MLA | You, Zhonglu,et al."Synthesis, structures, and insulin-like activity of oxidovanadium(V) complexes derived from 2-chloro-N '-(3-ethoxy-2-hydroxybenzylidene)benzohydrazide".JOURNAL OF COORDINATION CHEMISTRY 69.8(2016):1371-1379. |
入库方式： OAI收割
来源：大连化学物理研究所
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