Rh(III)-Catalyzed Synthesis of N-Unprotected Indoles from Imidamides and Diazo Ketoesters via C-H Activation and C-C/C-N Bond Cleavage
文献类型：期刊论文
| 作者 | Li, Xingwei; Qi, Zisong; Yu, Songjie |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2016-02-19 |
| 卷号 | 18期号:4页码:700-703 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/acs.orglett.5b03669 |
| 文献子类 | Article |
| 英文摘要 | The synthesis of N-unprotected indoles has been realized via Rh(III)-catalyzed C-H activation/annulation of imidamides with alpha-diazo beta-ketoesters. The reaction occurs with the release of an amide coproduct, which originates from both the imidamide and the diazo as a result of C=N cleavage of the imidamide and C-C(acyl) cleavage of the diazo. A rhodacyclic intermediate has been isolated and a plausible mechanism has been proposed. |
| WOS关键词 | NONREARRANGED MONOTERPENOID UNIT ; PALLADIUM-CATALYZED REACTIONS ; 2,3-DISUBSTITUTED INDOLES ; ONE-POT ; REGIOSPECIFIC SYNTHESIS ; C(SP(3))-H ACTIVATION ; SUBSTITUTED INDOLES ; INTERNAL ALKYNES ; COMPOUNDS ACCESS ; DIRECTING GROUP |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000370768200019 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/171300]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Li, Xingwei |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Xingwei,Qi, Zisong,Yu, Songjie. Rh(III)-Catalyzed Synthesis of N-Unprotected Indoles from Imidamides and Diazo Ketoesters via C-H Activation and C-C/C-N Bond Cleavage[J]. ORGANIC LETTERS,2016,18(4):700-703. |
| APA | Li, Xingwei,Qi, Zisong,&Yu, Songjie.(2016).Rh(III)-Catalyzed Synthesis of N-Unprotected Indoles from Imidamides and Diazo Ketoesters via C-H Activation and C-C/C-N Bond Cleavage.ORGANIC LETTERS,18(4),700-703. |
| MLA | Li, Xingwei,et al."Rh(III)-Catalyzed Synthesis of N-Unprotected Indoles from Imidamides and Diazo Ketoesters via C-H Activation and C-C/C-N Bond Cleavage".ORGANIC LETTERS 18.4(2016):700-703. |
入库方式： OAI收割
来源：大连化学物理研究所
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