Recent advances in lipidomics for disease research
文献类型：期刊论文
| 作者 | Li, Min1; Shen, Sensen1; Liu, Huwei1; Bai, Yu1; Yang, Li1; Shan, Yabing1,2 |
| 刊名 | JOURNAL OF SEPARATION SCIENCE
 |
| 出版日期 | 2016 |
| 卷号 | 39期号:1页码:38-50 |
| 关键词 | Biomarkers Clinical Diagnosis Lipidomics Metabolism |
| ISSN号 | 1615-9306 |
| DOI | 10.1002/jssc.201500899 |
| 文献子类 | Review |
| 英文摘要 | Lipidomics is an important branch of metabolomics, which aims at the detailed analysis of lipid species and their multiple roles in the living system. In recent years, the development of various analytical methods for effective identification and characterization of lipids has greatly promoted the process of lipidomics. Meanwhile, as many diseases demonstrate a remarkable alteration in lipid profiles compared with that of healthy people, lipidomics has been extensively introduced to disease research. The comprehensive lipid profiling provides a chance to discover novel biomarkers for specific disease. In addition, it plays a crucial role in the study of lipid metabolism, which could illuminate the pathogenesis of diseases. In this review, after brief discussion of analytical methods for lipidomics in clinical research, we focus on the recent advances of lipidomics related to four types of diseases, including cancer, atherosclerosis, diabetes mellitus, and Alzheimer's disease. |
| WOS关键词 | DESORPTION ELECTROSPRAY-IONIZATION ; 2-DIMENSIONAL GAS-CHROMATOGRAPHY ; IMAGING MASS-SPECTROMETRY ; PERITONEAL-DIALYSIS PATIENTS ; FATTY-ACID SYNTHASE ; LC-QTOF-MS ; ALZHEIMERS-DISEASE ; SHOTGUN LIPIDOMICS ; BREAST-CANCER ; HUMAN PLASMA |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000368876500004 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/171312]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Liu, Huwei |
| 作者单位 | 1.Peking Univ, Beijing Natl Lab Mol Sci, Key Lab Bioorgan Chem & Mol Engn, Minist Educ,Inst Analyt Chem,Coll Chem & Mol Engn, Beijing 100871, Peoples R China 2.Natl Res Ctr Geoanal, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Min,Shen, Sensen,Liu, Huwei,et al. Recent advances in lipidomics for disease research[J]. JOURNAL OF SEPARATION SCIENCE,2016,39(1):38-50. |
| APA | Li, Min,Shen, Sensen,Liu, Huwei,Bai, Yu,Yang, Li,&Shan, Yabing.(2016).Recent advances in lipidomics for disease research.JOURNAL OF SEPARATION SCIENCE,39(1),38-50. |
| MLA | Li, Min,et al."Recent advances in lipidomics for disease research".JOURNAL OF SEPARATION SCIENCE 39.1(2016):38-50. |
入库方式： OAI收割
来源：大连化学物理研究所
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