Comparative investigation of the binding characteristics of poly-L-lysine and chitosan on alginate hydrogel
文献类型：期刊论文
| 作者 | Ren, Ying2,3; Xie, Hongguo3; Liu, Xiaocen2,3; Bao, Jie1; Yu, Weiting3; Ma, Xiaojun3 |
| 刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
 |
| 出版日期 | 2016-03-01 |
| 卷号 | 84页码:135-141 |
| 关键词 | Alginate Chitosan Poly-l-lysine |
| ISSN号 | 0141-8130 |
| DOI | 10.1016/j.ijbiomac.2015.12.008 |
| 文献子类 | Article |
| 英文摘要 | The binding properties of poly-L-lysine and chitosan to alginate have been evaluated quantitatively and compared. Poly-L-lysine bound to alginate hydrogel more rapidly than chitosan as poly-L-lysine has a smaller molar hydrodynamic volume. In addition, poly-L-lysine showed a much higher binding capacity (6.14:1) for alginate hydrogel beads than chitosan (2.71:1), and a little higher binding stoichiometry (0.58) to sodium alginate molecules in solution than chitosan (0.49). An exothermic heat of alginate-poly-L-lysine complexes formation of 2.02 kJ/mol was detected. For alginate-chitosan complexes, the binding enthalpy has been seen to be -3.49 kJ/mol. The stability of the polyelectrolyte complexes was related to their binding enthalpy. The alginate-poly-L-lysine complexes could be disintegrated and rebuilt. By contrast, chitosan was bound with alginate in a steady state. These results provide fundamental insights regarding the structure and property relationships of macromolecules, and will be helpful in designing and selecting appropriate polymers. (C) 2015 Published by Elsevier B.V. |
| WOS关键词 | POLYELECTROLYTE MULTILAYERS ; DRUG-DELIVERY ; MICROCAPSULES ; COMPLEXATION ; POLYCATION ; MICROSCOPY ; STABILITY ; MICROGELS ; PEPTIDE ; GROWTH |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry ; Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000369456800018 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/171388]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Xie, Hongguo; Yu, Weiting |
| 作者单位 | 1.E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, 457 Zhongshan Rd, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ren, Ying,Xie, Hongguo,Liu, Xiaocen,et al. Comparative investigation of the binding characteristics of poly-L-lysine and chitosan on alginate hydrogel[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2016,84:135-141. |
| APA | Ren, Ying,Xie, Hongguo,Liu, Xiaocen,Bao, Jie,Yu, Weiting,&Ma, Xiaojun.(2016).Comparative investigation of the binding characteristics of poly-L-lysine and chitosan on alginate hydrogel.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,84,135-141. |
| MLA | Ren, Ying,et al."Comparative investigation of the binding characteristics of poly-L-lysine and chitosan on alginate hydrogel".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 84(2016):135-141. |
入库方式： OAI收割
来源：大连化学物理研究所
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