A turn-on fluorescent chemodosimeter based on detelluration for detecting ferrous iron (Fe2+) in living cells
文献类型：期刊论文
| 作者 | Qu, Zongjin1,2; Li, Peng2; Zhang, Xuexiang1,2; Han, Keli2 |
| 刊名 | JOURNAL OF MATERIALS CHEMISTRY B
 |
| 出版日期 | 2016 |
| 卷号 | 4期号:5页码:887-892 |
| ISSN号 | 2050-750X |
| DOI | 10.1039/c5tb02090e |
| 文献子类 | Article |
| 英文摘要 | A turn-on fluorescent probe for the detection of Fe2+ is facilely synthesized via a nucleophile substitution reaction. The fluorescent probe, N-butyl-4-phenyltellanyl-1,8-naphthalimide (Naph-Te), shows excellent selectivity to Fe2+ in a mixed solution of acetonitrile and phosphate buffer under aerobic conditions. The coexistence of biological abundant metal ions such as Na+, K+, Ca2+ and Mg2+ has little effect on the fluorescence signal. This turn-on response is achieved via a redox-involved reaction triggered by Fe2+ at neutral pH and room temperature, which removes the heavy-atom effect of the tellurium atom on the naphthalimide fluorophore to afford a fluorescent product (N-butyl-4-hydroxyl-1,8-naphthalimide). The probe has excellent cell membrane permeability and is further applied successfully to monitor supplementary Fe2+ in live HL-7702 cells using a laser confocal fluorescence microscope. |
| WOS关键词 | LABILE IRON ; CHELATABLE IRON ; SELECTIVE DETERMINATION ; OXIDATIVE STRESS ; K562 CELLS ; ZINC ION ; PROBE ; POOL ; SENSOR ; PEROXYNITRITE |
| WOS研究方向 | Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000369608000008 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/171398]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Han, Keli |
| 作者单位 | 1.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, 457 Zhongshan Rd, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qu, Zongjin,Li, Peng,Zhang, Xuexiang,et al. A turn-on fluorescent chemodosimeter based on detelluration for detecting ferrous iron (Fe2+) in living cells[J]. JOURNAL OF MATERIALS CHEMISTRY B,2016,4(5):887-892. |
| APA | Qu, Zongjin,Li, Peng,Zhang, Xuexiang,&Han, Keli.(2016).A turn-on fluorescent chemodosimeter based on detelluration for detecting ferrous iron (Fe2+) in living cells.JOURNAL OF MATERIALS CHEMISTRY B,4(5),887-892. |
| MLA | Qu, Zongjin,et al."A turn-on fluorescent chemodosimeter based on detelluration for detecting ferrous iron (Fe2+) in living cells".JOURNAL OF MATERIALS CHEMISTRY B 4.5(2016):887-892. |
入库方式： OAI收割
来源：大连化学物理研究所
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