中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
N-doped carbon dots derived from bovine serum albumin and formic acid with one- and two-photon fluorescence for live cell nuclear imaging

文献类型:期刊论文

作者Tan, Mingqian2; Li, Xintong1,3; Wu, Hao1; Wang, Beibei1; Wu, Jing3
刊名COLLOIDS AND SURFACES B-BIOINTERFACES
出版日期2015-12-01
卷号136页码:141-149
ISSN号0927-7765
关键词Carbon Dots Two-photon-induced Fluorescence Bioimaging Nitrogen-doped Nuclear-targeted Imaging
DOI10.1016/j.colsurfb.2015.09.008
文献子类Article
英文摘要Carbon dots with both one- and two-photon fluorescence have drawn great attention for biomedical imaging. Herein, nitrogen-doped carbon dots were facilely developed by one-pot hydrothermal method using bovine serum albumin and formic acid as carbon sources. They are highly water-soluble with strong fluorescence when excited with ultraviolet or near infrared light. The carbon dots have a diameter of similar to 8.32 nm and can emit strong two-photon induced fluorescence upon excitation at 750 nm with a femtosecond laser. X-ray photoelectron spectrometer analysis revealed that the carbon dots contained three components, C, N and 0, corresponding to the peak at 285, 398 and 532 eV, respectively. The Fourier-transform infrared spectroscopy analysis revealed that there are carboxyl and carboxylic groups on the surface, which allowed further linking of functional molecules. pH stability study demonstrated that the carbon dots are able to be used in a wide range of pH values. The fluorescence mechanism is also discussed in this study. Importantly, these carbon dots are biocompatible and highly photostable, which can be directly applied for both one- and two-photon living cell imaging. After proper surface functionalization with TAT peptide, they can be used as fluorescent probes for live cell nuclear-targeted imaging. (C) 2015 Elsevier B.V. All rights reserved.
WOS关键词ONE-STEP SYNTHESIS ; QUANTUM DOTS ; POLYETHYLENE-GLYCOL ; FACILE SYNTHESIS ; GREEN SYNTHESIS ; PHOTOLUMINESCENCE ; NITROGEN ; LUMINESCENCE
WOS研究方向Biophysics ; Chemistry ; Materials Science
语种英语
出版者ELSEVIER SCIENCE BV
WOS记录号WOS:000367408100019
源URL[http://cas-ir.dicp.ac.cn/handle/321008/171514]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者Tan, Mingqian
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China
2.Dalian Polytech Univ, Sch Food Sci & Technol, Natl Engn Res Ctr Seafood, Liaoning Prov Key Lab Seafood Sci & Technol, Dalian 116034, Peoples R China
3.Liaoning Normal Univ, Sch Chem & Chem Engn, Dalian 116029, Peoples R China
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GB/T 7714
Tan, Mingqian,Li, Xintong,Wu, Hao,et al. N-doped carbon dots derived from bovine serum albumin and formic acid with one- and two-photon fluorescence for live cell nuclear imaging[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2015,136:141-149.
APA Tan, Mingqian,Li, Xintong,Wu, Hao,Wang, Beibei,&Wu, Jing.(2015).N-doped carbon dots derived from bovine serum albumin and formic acid with one- and two-photon fluorescence for live cell nuclear imaging.COLLOIDS AND SURFACES B-BIOINTERFACES,136,141-149.
MLA Tan, Mingqian,et al."N-doped carbon dots derived from bovine serum albumin and formic acid with one- and two-photon fluorescence for live cell nuclear imaging".COLLOIDS AND SURFACES B-BIOINTERFACES 136(2015):141-149.

入库方式: OAI收割

来源:大连化学物理研究所

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