Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan
文献类型：期刊论文
| 作者 | Khan A4,5; Xin Wei X2,3,4; wangyifen@mail.kib.ac.cn; : xdluo@mail.kib.ac.cn; Liu YP2,4; Dai Z1,3; Song D6; Luo XD*2,4; Wang YF*2,4; Zhao XD1 |
| 刊名 | Natural Products and Bioprospecting
 |
| 出版日期 | 2017 |
| 卷号 | *期号:1-5页码:Pubished online |
| 关键词 | Apocynaceae Cytotoxicity Pyridine Alkaloids Vinca Major |
| 英文摘要 | Three new pyridine type alkaloids, (-)-vinmajpyridines A-C (1-3), along with two known alkaloids, have been isolated from the aerial parts of Vinca major cultivated in Pakistan. Their structures have been elucidated by means of NMR and HRESIMS spectroscopic data. The new alkaloids were evaluated for their cytotoxicity against glioma initiating cell lines (GITC-3# and GITC-18#), glioblastoma cell lines (U-87MG and T98G), and lung cancer cell line A-549, but none of them was active at 20 μg/mL concentration. |
| 语种 | 英语 |
| 资助机构 | The authors are grateful to the National Natural Science Foundation of China (81225024) for financial support. ; The authors are grateful to the National Natural Science Foundation of China (81225024) for financial support. ; The authors are grateful to the National Natural Science Foundation of China (81225024) for financial support. ; The authors are grateful to the National Natural Science Foundation of China (81225024) for financial support. |
| 源URL | [http://159.226.149.26:8080/handle/152453/11741]  |
| 专题 | 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 昆明动物研究所_肿瘤干细胞生物学 |
| 通讯作者 | wangyifen@mail.kib.ac.cn; : xdluo@mail.kib.ac.cn |
| 作者单位 | 1.Key Laboratory of Animal Models and Human Disease Mechanisms, Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, Yunnan, People’s Republic of China 2.Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming 650201, People’s Republic of China 3.University of Chinese Academy of Sciences, Beijing 100049, People’s Republic of China 4.State Key Laboratory of Phytochemistry and Plant Resources of West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People’s Republic of China 5.Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan 6.Yunnan College of Business Management, Kunming 650106, People’s Republic of China |
| 推荐引用方式 GB/T 7714 | Khan A,Xin Wei X,wangyifen@mail.kib.ac.cn,et al. Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan[J]. Natural Products and Bioprospecting,2017,*(1-5):Pubished online. |
| APA | Khan A.,Xin Wei X.,wangyifen@mail.kib.ac.cn.,: xdluo@mail.kib.ac.cn.,Liu YP.,...&Yu HF.(2017).Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan.Natural Products and Bioprospecting,*(1-5),Pubished online. |
| MLA | Khan A,et al."Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan".Natural Products and Bioprospecting *.1-5(2017):Pubished online. |
入库方式： OAI收割
来源：昆明动物研究所
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