中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus.

文献类型:期刊论文

作者Li-Dong Shao; Xiao-Nian Li; Jian Yang; Luo-Sheng Wan; Ming Zhou; Ming-Hua Qiu; Xing-Rong Peng
刊名Organic Letters
出版日期2018
期号20页码:3074−3078
DOI10.1021/acs.orglett.8b01114
英文摘要

Pepluanols C and D (1 and 2), featuringunprecedented 5/5/10 with out,out-[7.2.1]bicylcododecanecore and 6/6/7/3 fused-ring skeletons, respectively, wereisolated from Euphorbia peplus. Their chemical structures andabsolute configurations were determined by a series ofextensive spectroscopic methods, and X-ray diffractionanalysis. In addition, pepluanols C and D showed 31.6 ±8.3% and 30.5 ± 2.8% peak current inhibition on the K v 1.3potassium channel at 30 μM.

语种英语
源URL[http://159.226.149.26:8080/handle/152453/12339]  
专题昆明动物研究所_离子通道药物研发中心
通讯作者Ming Zhou
作者单位1.Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, United States
2.Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Pharmacy Department of Tongji Medical School, Huazhong University of Science and Technology, Wuhan 430030, P. R. China
3.Key Laboratory of Animal Models and Human Diease Mechanisms, and Ion Channel Research and Drug Development Center, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, P. R. China
4.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China
推荐引用方式
GB/T 7714
Li-Dong Shao,Xiao-Nian Li,Jian Yang,et al. Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus.[J]. Organic Letters,2018(20):3074−3078.
APA Li-Dong Shao.,Xiao-Nian Li.,Jian Yang.,Luo-Sheng Wan.,Ming Zhou.,...&Xing-Rong Peng.(2018).Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus..Organic Letters(20),3074−3078.
MLA Li-Dong Shao,et al."Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus.".Organic Letters .20(2018):3074−3078.

入库方式: OAI收割

来源:昆明动物研究所

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