Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus.
文献类型:期刊论文
作者 | Li-Dong Shao; Xiao-Nian Li; Jian Yang; Luo-Sheng Wan; Ming Zhou; Ming-Hua Qiu; Xing-Rong Peng |
刊名 | Organic Letters
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出版日期 | 2018 |
期号 | 20页码:3074−3078 |
DOI | 10.1021/acs.orglett.8b01114 |
英文摘要 | Pepluanols C and D (1 and 2), featuringunprecedented 5/5/10 with out,out-[7.2.1]bicylcododecanecore and 6/6/7/3 fused-ring skeletons, respectively, wereisolated from Euphorbia peplus. Their chemical structures andabsolute configurations were determined by a series ofextensive spectroscopic methods, and X-ray diffractionanalysis. In addition, pepluanols C and D showed 31.6 ±8.3% and 30.5 ± 2.8% peak current inhibition on the K v 1.3potassium channel at 30 μM. |
语种 | 英语 |
源URL | [http://159.226.149.26:8080/handle/152453/12339] ![]() |
专题 | 昆明动物研究所_离子通道药物研发中心 |
通讯作者 | Ming Zhou |
作者单位 | 1.Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, United States 2.Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Pharmacy Department of Tongji Medical School, Huazhong University of Science and Technology, Wuhan 430030, P. R. China 3.Key Laboratory of Animal Models and Human Diease Mechanisms, and Ion Channel Research and Drug Development Center, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, P. R. China 4.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China |
推荐引用方式 GB/T 7714 | Li-Dong Shao,Xiao-Nian Li,Jian Yang,et al. Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus.[J]. Organic Letters,2018(20):3074−3078. |
APA | Li-Dong Shao.,Xiao-Nian Li.,Jian Yang.,Luo-Sheng Wan.,Ming Zhou.,...&Xing-Rong Peng.(2018).Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus..Organic Letters(20),3074−3078. |
MLA | Li-Dong Shao,et al."Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus.".Organic Letters .20(2018):3074−3078. |
入库方式: OAI收割
来源:昆明动物研究所
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