中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Identification of bacteria by a fluorescence sensor array based on three kinds of receptors functionalized carbon dots

文献类型:期刊论文

作者Zheng, Laibao1,2,3,4; Qi, Peng1,2,4; Zhang, Dun1,2,4
刊名SENSORS AND ACTUATORS B-CHEMICAL
出版日期2019-05-01
卷号286页码:206-213
关键词Bacterial identification Sensor array Carbon dots Cross-reactive receptors Pattern recognition
ISSN号0925-4005
DOI10.1016/j.snb.2019.01.147
通讯作者Qi, Peng(qipeng@qdio.ac.cn) ; Zhang, Dun(zhangdun@qdio.ac.cn)
英文摘要The identification of bacteria is a crucial issue in the field of medical diagnosis, environmental monitoring and food safety. Conventional methods need long culturing times, highly skilled operators, or recognition elements specific to each kind of the bacteria. Alternatively, sensor arrays offer a cost-effective and simple approach using multiple cross-reactive receptors. Here, a facilely constructed fluorescence sensing array was developed for the identification of various bacteria. The sensor array consists of three facile synthesized carbon dots functionalized with different receptors (boronic acid, polymixin and vancomycin), which could bind to all the bacteria with different affinity instead of a specific one. A unique molecular fingerprint of each kind of bacteria was obtain from the fluorescence response pattern generated from three kinds of carbon dots. By using linear discrimination analysis (LDA) of the response pattern, the effective discrimination of six bacteria studied was demonstrated. The proposed sensor array approach may pave the way for the development of simple, rapid and effective identification of multiplex bioactive samples.
资助项目National Natural Science Foundation of China[41876101] ; Young Elite Scientists Sponsorship Program by CAST[2018QNRC001] ; Applied Basic Research Program of Nantong[GY12017005] ; AoShan Talent Program ; Qingdao National Laboratory for Marine Science and Technology[017ASTCP-ES02]
WOS研究方向Chemistry ; Electrochemistry ; Instruments & Instrumentation
语种英语
WOS记录号WOS:000459129600028
出版者ELSEVIER SCIENCE SA
源URL[http://ir.qdio.ac.cn/handle/337002/155578]  
专题海洋研究所_海洋腐蚀与防护研究发展中心
通讯作者Qi, Peng; Zhang, Dun
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Environm Corros & Biofouling, 7 Nanhai Rd, Qingdao 266071, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Open Studio Marine Corros & Protect, 1 Wenhai Rd, Qingdao 266237, Peoples R China
3.Univ Chinese Acad Sci, 19 Jia Yuquan Rd, Beijing 100039, Peoples R China
4.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China
推荐引用方式
GB/T 7714
Zheng, Laibao,Qi, Peng,Zhang, Dun. Identification of bacteria by a fluorescence sensor array based on three kinds of receptors functionalized carbon dots[J]. SENSORS AND ACTUATORS B-CHEMICAL,2019,286:206-213.
APA Zheng, Laibao,Qi, Peng,&Zhang, Dun.(2019).Identification of bacteria by a fluorescence sensor array based on three kinds of receptors functionalized carbon dots.SENSORS AND ACTUATORS B-CHEMICAL,286,206-213.
MLA Zheng, Laibao,et al."Identification of bacteria by a fluorescence sensor array based on three kinds of receptors functionalized carbon dots".SENSORS AND ACTUATORS B-CHEMICAL 286(2019):206-213.

入库方式: OAI收割

来源:海洋研究所

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