Involvement of clustered oyster Wnt genes in gut formation
文献类型:期刊论文
作者 | Liu Jun1,2,4; Xu Fei1,3,4; Ji Peng1,2,4![]() |
刊名 | JOURNAL OF OCEANOLOGY AND LIMNOLOGY
![]() |
出版日期 | 2018-09-01 |
卷号 | 36期号:5页码:1746-1752 |
关键词 | gene cluster tissue distribution digestive gland immunofluorescence Crassostrea gigas |
ISSN号 | 2096-5508 |
DOI | 10.1007/s00343-018-7138-1 |
通讯作者 | Xu Fei(xufei@qdio.ac.cn) ; Zhang Guofan(gfzhang@qdio.ac.cn) |
英文摘要 | Genes encoding Wnt ligands play important roles in organ development. The Wnt10-Wnt6-Wnt1-Wnt9 cluster widely presents in many metazoan genomes, indicating the importance of gene arrangement. Hypothesis has been proposed that they may be coordinately regulated. However, few expression correlations were identified in model animals. We analyzed the tissue expression pattern of clustered oyster Wnt10, Wnt6, Wnt1, and Wnt9a genes in this study. The results indicated the highest expression level in adult gut system of these clustered Wnt genes, except for Wnt6, which had highest expression in mantle. Further whole-mount immunofluorescence assay indicated that Wnt6 protein was restricted to gut region in oyster larvae. These results suggest the possible important role of the Wnt10-Wnt6-Wnt1-Wnt9 cluster in oyster gut formation. |
资助项目 | National Natural Science Foundation of China[41776152] ; National Natural Science Foundation of China[31402285] ; National Natural Science Foundation of China[31530079] ; Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; earmarked fund for Modern Agro-industry Technology Research System[CARS-49] ; Scientific and Technological Innovation Project |
WOS研究方向 | Marine & Freshwater Biology ; Oceanography |
语种 | 英语 |
WOS记录号 | WOS:000450165300025 |
出版者 | SCIENCE PRESS |
源URL | [http://ir.qdio.ac.cn/handle/337002/156412] ![]() |
专题 | 海洋研究所_实验海洋生物学重点实验室 |
通讯作者 | Xu Fei; Zhang Guofan |
作者单位 | 1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266000, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China 5.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries & Aquaculture, Qingdao 266000, Peoples R China |
推荐引用方式 GB/T 7714 | Liu Jun,Xu Fei,Ji Peng,et al. Involvement of clustered oyster Wnt genes in gut formation[J]. JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2018,36(5):1746-1752. |
APA | Liu Jun,Xu Fei,Ji Peng,Li Li,&Zhang Guofan.(2018).Involvement of clustered oyster Wnt genes in gut formation.JOURNAL OF OCEANOLOGY AND LIMNOLOGY,36(5),1746-1752. |
MLA | Liu Jun,et al."Involvement of clustered oyster Wnt genes in gut formation".JOURNAL OF OCEANOLOGY AND LIMNOLOGY 36.5(2018):1746-1752. |
入库方式: OAI收割
来源:海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。