中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Involvement of clustered oyster Wnt genes in gut formation

文献类型:期刊论文

作者Liu Jun1,2,4; Xu Fei1,3,4; Ji Peng1,2,4; Li Li1,4,5; Zhang Guofan1,3,4
刊名JOURNAL OF OCEANOLOGY AND LIMNOLOGY
出版日期2018-09-01
卷号36期号:5页码:1746-1752
关键词gene cluster tissue distribution digestive gland immunofluorescence Crassostrea gigas
ISSN号2096-5508
DOI10.1007/s00343-018-7138-1
通讯作者Xu Fei(xufei@qdio.ac.cn) ; Zhang Guofan(gfzhang@qdio.ac.cn)
英文摘要Genes encoding Wnt ligands play important roles in organ development. The Wnt10-Wnt6-Wnt1-Wnt9 cluster widely presents in many metazoan genomes, indicating the importance of gene arrangement. Hypothesis has been proposed that they may be coordinately regulated. However, few expression correlations were identified in model animals. We analyzed the tissue expression pattern of clustered oyster Wnt10, Wnt6, Wnt1, and Wnt9a genes in this study. The results indicated the highest expression level in adult gut system of these clustered Wnt genes, except for Wnt6, which had highest expression in mantle. Further whole-mount immunofluorescence assay indicated that Wnt6 protein was restricted to gut region in oyster larvae. These results suggest the possible important role of the Wnt10-Wnt6-Wnt1-Wnt9 cluster in oyster gut formation.
资助项目National Natural Science Foundation of China[41776152] ; National Natural Science Foundation of China[31402285] ; National Natural Science Foundation of China[31530079] ; Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; earmarked fund for Modern Agro-industry Technology Research System[CARS-49] ; Scientific and Technological Innovation Project
WOS研究方向Marine & Freshwater Biology ; Oceanography
语种英语
WOS记录号WOS:000450165300025
出版者SCIENCE PRESS
源URL[http://ir.qdio.ac.cn/handle/337002/156412]  
专题海洋研究所_实验海洋生物学重点实验室
通讯作者Xu Fei; Zhang Guofan
作者单位1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266000, Peoples R China
4.Chinese Acad Sci, Inst Oceanol, Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China
5.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries & Aquaculture, Qingdao 266000, Peoples R China
推荐引用方式
GB/T 7714
Liu Jun,Xu Fei,Ji Peng,et al. Involvement of clustered oyster Wnt genes in gut formation[J]. JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2018,36(5):1746-1752.
APA Liu Jun,Xu Fei,Ji Peng,Li Li,&Zhang Guofan.(2018).Involvement of clustered oyster Wnt genes in gut formation.JOURNAL OF OCEANOLOGY AND LIMNOLOGY,36(5),1746-1752.
MLA Liu Jun,et al."Involvement of clustered oyster Wnt genes in gut formation".JOURNAL OF OCEANOLOGY AND LIMNOLOGY 36.5(2018):1746-1752.

入库方式: OAI收割

来源:海洋研究所

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