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Antioxidant Hydroanthraquinones from the Marine Algal-Derived Endophytic Fungus Talaromyces islandicus EN-501

文献类型：期刊论文

作者Li, Hong-Lei1,2; Li, Xiao-Ming1; Li, Xin1,2; Wang, Chen-Yin3; Liu, Hui1,2; Kassack, Matthias U.3; Meng, Ling-Hong1; Wang, Bin-Gui1
刊名JOURNAL OF NATURAL PRODUCTS
出版日期2017
卷号80期号:1页码:162-168
ISSN号0163-3864
DOI10.1021/acs.jnatprod.6b00797
通讯作者Kassack, Matthias U.(Matthias.Kassack@uni-duesseldorf.de) ; Meng, Ling-Hong(menglh@ms.qdio.ac.cn) ; Wang, Bin-Gui(wangbg@ms.qdio.ac.cn)
英文摘要Five new polyhydroxylated hydroanthraquinone derivatives, namely, 8-hydroxyconiothyrinone B (1), 8,11-dihydroxyconiothyrinone B (2), 4R,8-dihydroxyconiothyrinone B (3), 4S,8-dihydroxyconiothyrinone B (4), and 4S,8-dihydroxy-10-O-methyldendryol E (5), were isolated and identified from the culture extract of Talaromyces islandicus EN-501, an endophytic fungus obtained from the inner tissue of the marine red alga Laurencia okamurai. The structures of these compounds were established on the basis of detailed interpretation of their NMR and mass spectroscopic data, and the structures and absolute configurations of compounds 1 and 2 were confirmed by X-ray crystallographic analysis, while the absolute configurations of compounds 3-5 were determined by TDDFT calculations of the ECD spectra. The antimicrobial, antioxidant, and cytotoxic activities of compounds 1-5 were evaluated.
资助项目Natural Science Foundation of China[31330009] ; Scientific and Technological Innovation Project of Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; Taishan Scholar Project from Shandong Province of China ; Bundesminsterium fur Forschung (BMBF, Germany)[BMBF-16GW0108]
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000393089600022
出版者AMER CHEMICAL SOC
源URL[http://ir.qdio.ac.cn/handle/337002/157266]  
专题海洋研究所_实验海洋生物学重点实验室
通讯作者Kassack, Matthias U.; Meng, Ling-Hong; Wang, Bin-Gui
作者单位1.Chinese Acad Sci, Lab Marine Biol & Biotechnol, Qmgdao Natl Lab Marine Sci & Technol, Key Lab Expt Marine Biol,Inst Oceanol, Nanhai Rd 7, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China
3.Heinrich Heine Univ Dusseldorf, Inst Pharmazeut & Med Chem, Univ Str 1, D-40225 Dusseldorf, Germany
推荐引用方式
GB/T 7714		 Li, Hong-Lei,Li, Xiao-Ming,Li, Xin,et al. Antioxidant Hydroanthraquinones from the Marine Algal-Derived Endophytic Fungus Talaromyces islandicus EN-501[J]. JOURNAL OF NATURAL PRODUCTS,2017,80(1):162-168.
APA Li, Hong-Lei.,Li, Xiao-Ming.,Li, Xin.,Wang, Chen-Yin.,Liu, Hui.,...&Wang, Bin-Gui.(2017).Antioxidant Hydroanthraquinones from the Marine Algal-Derived Endophytic Fungus Talaromyces islandicus EN-501.JOURNAL OF NATURAL PRODUCTS,80(1),162-168.
MLA Li, Hong-Lei,et al."Antioxidant Hydroanthraquinones from the Marine Algal-Derived Endophytic Fungus Talaromyces islandicus EN-501".JOURNAL OF NATURAL PRODUCTS 80.1(2017):162-168.

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来源：海洋研究所

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