Antimicrobial polyketides from Trichoderma koningiopsis QA-3, an endophytic fungus obtained from the medicinal plant Artemisia argyi
文献类型：期刊论文
| 作者 | Shi, Xiao-Shan1,2,3 ; Wang, Dun-Jia2; Li, Xiao-Ming1; Li, Hong-Lei1; Meng, Ling-Hong1; Li, Xin1; Pi, Yan2; Zhou, Xing-Wang2; Wang, Bin-Gui1
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| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:81页码:51335-51342 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c7ra11122c |
| 通讯作者 | Zhou, Xing-Wang(228689100@qq.com) ; Wang, Bin-Gui(wangbg@ms.qdio.ac.cn) |
| 英文摘要 | Artemisia argyi is broadly cultivated as a medicinal plant in Qichun of Hubei province in central China. Five new fungal polyketides (1-5) and two known analogues (6 and 7) were isolated and identified from the culture extract of Trichoderma koningiopsis QA-3, an endophytic fungus obtained from the inner tissue of Artemisia argyi that was collected from Qichun. Their structures were elucidated by detailed interpretation of the spectroscopic data and the structures and absolute configurations of compounds 1-4 were confirmed by X-ray crystallographic analysis. Compounds 1-3 are tricyclic polyketides possessing octahydrochromene framework and having ketal unit in their structures, while compounds 4/7 and 5/6 are related bicyclic and tricyclic analogues, respectively. The antibacterial activities against human pathogen E. coli and seven marine-derived aquatic pathogens as well as against eight agropathogenic fungi for each of the isolated compounds were evaluated. Compounds 1-7 showed activity against human pathogen Escherichia coli (each with MIC 64 mg mL(-1)), while 1 and 7 inhibited most of the tested aquatic bacteria and agro-pathogenic fungi (MICs ranging from 4 to 64 mg mL(-1)), respectively. |
| 资助项目 | Scientific and Technological Innovation Project of Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; Taishan Scholar Project from Shandong Province |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000414780700031 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/157272]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Zhou, Xing-Wang; Wang, Bin-Gui |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Key Lab Expt Marine Biol,Inst Oceanol, Nanhai Rd 7, Qingdao 266071, Peoples R China 2.Hubei Normal Univ, Coll Chem & Chem Engn, Cihu Rd 11, Huangshi 435002, Peoples R China 3.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shi, Xiao-Shan,Wang, Dun-Jia,Li, Xiao-Ming,et al. Antimicrobial polyketides from Trichoderma koningiopsis QA-3, an endophytic fungus obtained from the medicinal plant Artemisia argyi[J]. RSC ADVANCES,2017,7(81):51335-51342. |
| APA | Shi, Xiao-Shan.,Wang, Dun-Jia.,Li, Xiao-Ming.,Li, Hong-Lei.,Meng, Ling-Hong.,...&Wang, Bin-Gui.(2017).Antimicrobial polyketides from Trichoderma koningiopsis QA-3, an endophytic fungus obtained from the medicinal plant Artemisia argyi.RSC ADVANCES,7(81),51335-51342. |
| MLA | Shi, Xiao-Shan,et al."Antimicrobial polyketides from Trichoderma koningiopsis QA-3, an endophytic fungus obtained from the medicinal plant Artemisia argyi".RSC ADVANCES 7.81(2017):51335-51342. |
入库方式： OAI收割
来源：海洋研究所
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