RNA-seq based transcriptional analysis reveals dynamic genes expression profiles and immune-associated regulation under heat stress in Apostichopus japonicus
文献类型：期刊论文
| 作者 | Xu, Dongxue ; Zhou, Shun; Sun, Lina1
|
| 刊名 | FISH & SHELLFISH IMMUNOLOGY
 |
| 出版日期 | 2018-07-01 |
| 卷号 | 78页码:169-176 |
| 关键词 | Apostichopus japonicus Heat stress Differentially expressed genes Immune-associated genes |
| ISSN号 | 1050-4648 |
| DOI | 10.1016/j.fsi.2018.04.037 |
| 文献子类 | Article |
| 英文摘要 | In this study, we explored the gene expression profiles in Apostichopus japonicus under continuous heat stress (6 h, 48 h and 192 h) by applying RNA-seq technique. A total of 676, 1010 and 1083 differentially expressed genes were detected at three heat stress groups respectively, which suggested complex regulation of various biological processes. Then we focused on the changing of immune system under HS in sea cucumbers. Key immune-associated genes were involved in heat stress response, which were classified into six groups: heat shock proteins, transferrin superfamily members, effector genes, proteases, complement system, and pattern recognition receptors and signaling. Moreover, the mRNA expression of the immune-associated genes were validated by the real time PCR. Our results showed that an immunological strategy in this species was developed to confront abrupt elevated temperatures in the environment. |
| 学科主题 | Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences |
| WOS研究方向 | Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000437385000020 |
| 出版者 | ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/157559]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 作者单位 | 1.Qingdao Agr Univ, Coll Marine Sci & Engn, Qingdao 266109, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Dongxue,Zhou, Shun,Sun, Lina. RNA-seq based transcriptional analysis reveals dynamic genes expression profiles and immune-associated regulation under heat stress in Apostichopus japonicus[J]. FISH & SHELLFISH IMMUNOLOGY,2018,78:169-176. |
| APA | Xu, Dongxue,Zhou, Shun,&Sun, Lina.(2018).RNA-seq based transcriptional analysis reveals dynamic genes expression profiles and immune-associated regulation under heat stress in Apostichopus japonicus.FISH & SHELLFISH IMMUNOLOGY,78,169-176. |
| MLA | Xu, Dongxue,et al."RNA-seq based transcriptional analysis reveals dynamic genes expression profiles and immune-associated regulation under heat stress in Apostichopus japonicus".FISH & SHELLFISH IMMUNOLOGY 78(2018):169-176. |
入库方式： OAI收割
来源：海洋研究所
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