Fast screening of short-chain chlorinated paraffins in indoor dust samples by graphene-assisted laser desorption/ionization mass spectrometry
文献类型：期刊论文
| 作者 | Huang, Xiu; Liu, Qian; Gao, Wei ; Wang, Yawei; Nie, Zhou; Yao, Shouzhuo; Jiang, Guibin
|
| 刊名 | TALANTA
 |
| 出版日期 | 2018-03-01 |
| 卷号 | 179页码:575-582 |
| 关键词 | Matrix-assisted laser desorption/ionization Short-chain chlorinated paraffins Graphene Mass spectrometry Environmental sample |
| ISSN号 | 0039-9140 |
| 文献子类 | Article |
| 英文摘要 | As an important class of emerging chemical contaminants, short-chain chlorinated paraffins (SCCPs) are considered as one of the most challenging groups of compounds to analyze. In this paper, we report a new method for fast screening of SCCPs based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) with graphene as a matrix and 2,5,6,9-tetrachlorodecane as an internal standard. We found that the use of graphene as MALDI matrix generated high peak intensities for SCCPs while producing few background noises. The ion fragmentation mechanisms of SCCPs in MALDI are discussed in detail. Under the optimized conditions, much lower detection limits of SCCP congeners (0.1-5 ng/mL) than those reported previously were obtained. Other distinct advantages such as short analysis time and simplified sample preparation procedures are also demonstrated. The method was successfully applied in fast screening of SCCPs in indoor dust samples and monitoring of human exposure levels to SCCPs, and the results were verified by gas chromatography coupled to negative chemical ionization quadrupole time-of-flight high-resolution mass spectrometry. This work not only offers a new promising tool for SCCP studies, but also further demonstrates the promise of graphene as a new generation of MALDI matrix. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/40946]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Huang, Xiu,Liu, Qian,Gao, Wei,et al. Fast screening of short-chain chlorinated paraffins in indoor dust samples by graphene-assisted laser desorption/ionization mass spectrometry[J]. TALANTA,2018,179:575-582. |
| APA | Huang, Xiu.,Liu, Qian.,Gao, Wei.,Wang, Yawei.,Nie, Zhou.,...&Jiang, Guibin.(2018).Fast screening of short-chain chlorinated paraffins in indoor dust samples by graphene-assisted laser desorption/ionization mass spectrometry.TALANTA,179,575-582. |
| MLA | Huang, Xiu,et al."Fast screening of short-chain chlorinated paraffins in indoor dust samples by graphene-assisted laser desorption/ionization mass spectrometry".TALANTA 179(2018):575-582. |
入库方式： OAI收割
来源：生态环境研究中心
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