Simultaneous size characterization and mass quantification of the in vivo core-biocorona structure and dissolved species of silver nanoparticles
文献类型：期刊论文
| 作者 | Liu, Jingfu; Zhou, Xiaoxia; Dong, Lijie; Hu, Ligang; Yin, Yongguang |
| 刊名 | JOURNAL OF ENVIRONMENTAL SCIENCES
 |
| 出版日期 | 2018 |
| 卷号 | 63页码:227-235 |
| 关键词 | Silver nanoparticle In vivo study Size characterization Mass quantification Size exclusion chromatography |
| ISSN号 | 1001-0742 |
| 文献子类 | Article |
| 英文摘要 | Size characterization of silver nanoparticles with biomolecule corona (AgNP@BCs) and mass quantification of various silver species in organisms are essential for understanding the in vivo transformation of AgNPs. Herein, we report a versatile method that allows simultaneous determination of the size of AgNP@BCs and mass concentration of various silver species in rat liver. Both particulate and ionic silver were extracted in their original forms fromthe organs by alkaline digestion, and analyzed by size exclusion chromatography combined with inductively coupled plasma mass spectrometry (SEC-ICP-MS). While the silver mass concentrations were quantified by ICP-MS with a detection limit of 0.1 mu g/g, the effective diameter of AgNP@BCs was determined based on the retention time in SEC separation with size discrimination of 0.6-3.3 nm. More importantly, we found that the BC thickness of AgNP@BCs is core size independent, and a linear correlation was found between the effective diameter and core diameter of AgNP@BCs in extracted tissues, whichwas used to calibrate the core diameter with standard deviations in the range of 0.2-1.1 nm. The utility of this strategy was demonstrated through application to rat livers in vivo. Our method is powerful for investigating the transformation mechanism of AgNPs in vivo. (C) 2017 The Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences. Published by Elsevier B.V. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/41037]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Liu, Jingfu,Zhou, Xiaoxia,Dong, Lijie,et al. Simultaneous size characterization and mass quantification of the in vivo core-biocorona structure and dissolved species of silver nanoparticles[J]. JOURNAL OF ENVIRONMENTAL SCIENCES,2018,63:227-235. |
| APA | Liu, Jingfu,Zhou, Xiaoxia,Dong, Lijie,Hu, Ligang,&Yin, Yongguang.(2018).Simultaneous size characterization and mass quantification of the in vivo core-biocorona structure and dissolved species of silver nanoparticles.JOURNAL OF ENVIRONMENTAL SCIENCES,63,227-235. |
| MLA | Liu, Jingfu,et al."Simultaneous size characterization and mass quantification of the in vivo core-biocorona structure and dissolved species of silver nanoparticles".JOURNAL OF ENVIRONMENTAL SCIENCES 63(2018):227-235. |
入库方式： OAI收割
来源：生态环境研究中心
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