Speciation and bioaccessibility of arsenic in traditional Chinese medicines and assessment of its potential health risk
文献类型：期刊论文
| 作者 | Liu, Lihong; Zhang, Yu ; Yun, Zhaojun; He, Bin; Zhang, Qinghua; Hu, Ligang; Jiang, Guibin
|
| 刊名 | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| 出版日期 | 2018-04-01 |
| 卷号 | 619页码:1088-1097 |
| 关键词 | Traditional Chinese medicine Arsenic Speciation Bioaccessibility Simulated gastrointestinal digestion |
| ISSN号 | 0048-9697 |
| 文献子类 | Article |
| 英文摘要 | Arsenic in traditional Chinese medicines (TCMs) has caused public concerns about its health risk in recent years due to the high toxicity of arsenic and widespread use of those medicines throughout the world. However, in previous studies the arsenic toxicity was usually overestimated by considering the total arsenic concentration only. This work investigated the total concentration, speciation and bioaccessibility of arsenic in 84 commonly used traditional Chinese patent medicines (CPMs) and Chinese herbal medicines (CHMs) to evaluate arsenic's potential health risks to human. Arsenic was found in all the CPMs and 88% of CHMs at concentrations ranging from 0.033 to 91,000 mg kg(-1) and 0.012 to 6.6 mg kg(-1), respectively. The bioaccessibility of arsenic varied significantly and was in the range of 0.21%-90% in the CPMs and 15%-96% in the CHMs, with inorganic arsenic as the predominant species. The average daily intake dose (ADD) and hazard quotient (HQ) of arsenic inmost of medicines were within the safe limits, while in certain medicines, they exceeded the safe threshold level. These excesses remind us that the potential health risk by consumption of several medicines may not be negligible and more control and monitoring of arsenic in medicines should be carried out. (c) 2017 Elsevier B.V. All rights reserved. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/41047]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Liu, Lihong,Zhang, Yu,Yun, Zhaojun,et al. Speciation and bioaccessibility of arsenic in traditional Chinese medicines and assessment of its potential health risk[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2018,619:1088-1097. |
| APA | Liu, Lihong.,Zhang, Yu.,Yun, Zhaojun.,He, Bin.,Zhang, Qinghua.,...&Jiang, Guibin.(2018).Speciation and bioaccessibility of arsenic in traditional Chinese medicines and assessment of its potential health risk.SCIENCE OF THE TOTAL ENVIRONMENT,619,1088-1097. |
| MLA | Liu, Lihong,et al."Speciation and bioaccessibility of arsenic in traditional Chinese medicines and assessment of its potential health risk".SCIENCE OF THE TOTAL ENVIRONMENT 619(2018):1088-1097. |
入库方式： OAI收割
来源：生态环境研究中心
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