Ecotoxicological effects of binary mixtures of siduron and Cd on mRNA expression in the earthworm Eisenia fetida
文献类型：期刊论文
| 作者 | Uwizeyimana, Herman; Wang, Meie; Chen, Weiping ; Khan, Kifayatullah
|
| 刊名 | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| 出版日期 | 2018 |
| 卷号 | 610页码:657-665 |
| 关键词 | Siduron Cadmium Earthworm mRNA expression Joint effects Combination index |
| ISSN号 | 0048-9697 |
| 文献子类 | Article |
| 英文摘要 | This study aimed to investigate the eco-toxicological responses of earthworm (Eisenia fetida) exposed to combined siduron (herbicide) and cadmium (Cd). Eisenia fetida gene expressions including metallothionein (MT) and heat shock protein70 (Hsp70) were analyzed using real-time Polymerase Chain Reaction after individual and combined siduron (0.90, 1.80, 3.60 and 7.20 mu g cm(-2)) and Cd (0.225, 0.45, 0.90 and 1.80 mu g cm(-2)) sublethal exposures. Where, the nature of the toxicological interactions between siduron and Cd in inducing or suppressing MT and Hsp70 expression was determined by applying the Combination index (CI)-isobologram model. The results revealed significant variations in MT and weak changes in Hsp70 expression when the earthworms were exposed to individual Cd. The individual siduron exposure exhibited a significant down-regulation (p < 0.01) in MT during all treatments and in Hsp70 expression only at 7.20 mu g cm(-2) concentration; while the mixtures of siduron and Cd exposures resulted a significant down regulation (p < 0.05) in both MT and Hsp70 expressions. Moreover, the combined siduron and Cd exposure revealed nearly additive effect (CI = 1) at the lower effect levels and significant synergistic effect (CI < 1) at the higher effect levels for both MT and Hsp70 expression. The synergistic effects of combined siduron and Cd suggest that there might be a potential risk connected to the co-occurrence of these chemicals in the environment. (C) 2017 Elsevier B.V. All rights reserved. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/40530]  |
| 专题 | 生态环境研究中心_城市与区域生态国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Uwizeyimana, Herman,Wang, Meie,Chen, Weiping,et al. Ecotoxicological effects of binary mixtures of siduron and Cd on mRNA expression in the earthworm Eisenia fetida[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2018,610:657-665. |
| APA | Uwizeyimana, Herman,Wang, Meie,Chen, Weiping,&Khan, Kifayatullah.(2018).Ecotoxicological effects of binary mixtures of siduron and Cd on mRNA expression in the earthworm Eisenia fetida.SCIENCE OF THE TOTAL ENVIRONMENT,610,657-665. |
| MLA | Uwizeyimana, Herman,et al."Ecotoxicological effects of binary mixtures of siduron and Cd on mRNA expression in the earthworm Eisenia fetida".SCIENCE OF THE TOTAL ENVIRONMENT 610(2018):657-665. |
入库方式： OAI收割
来源：生态环境研究中心
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。