Tracking antibiotic resistome during wastewater treatment using high throughput quantitative PCR
文献类型：期刊论文
| 作者 | Zhao, Yi; Zhu, Yong-Guan; Zhang, Tong; Gillings, Michael R.; Chen, Hong; Cui, Li; Chen, Qing-Lin; Ouyang, Wei-Ying; Li, Bing; Su, Jian-Qiang |
| 刊名 | ENVIRONMENT INTERNATIONAL
 |
| 出版日期 | 2018-08-01 |
| 卷号 | 117页码:146-153 |
| 关键词 | Antibiotic resistance genes Human pathogens Horizontal gene transfer Human health Urban environment |
| ISSN号 | 0160-4120 |
| 文献子类 | Article |
| 英文摘要 | Wastewater treatment plants (WWTPs) contain diverse antibiotic resistance genes (ARGs), and thus are considered as a major pathway for the dissemination of these genes into the environments. However, comprehensive evaluations of ARGs dynamic during wastewater treatment process lack extensive investigations on a broad spectrum of ARGs. Here, we investigated the dynamics of ARGs and bacterial community structures in 114 samples from eleven Chinese WWTPs using high-throughput quantitative PCR and 16S rRNA-based Illumina sequencing analysis. Significant shift of ARGs profiles was observed and wastewater treatment process could significantly reduce the abundance and diversity of ARGs, with the removal of ARGs concentration by 1-2 orders of magnitude. Whereas, a considerable number of ARGs were detected and enriched in effluents compared with influents. In particular, seven ARGs mainly conferring resistance to beta-lactams and aminoglycosides and three mobile genetic elements persisted in all WWTPs samples after wastewater treatment. ARGs profiles varied with wastewater treatment processes, seasons and regions. This study tracked the footprint of ARGs during wastewater treatment process, which would support the assessment on the spread of ARGs from WWTPs and provide data for identifying management options to improve ARG mitigation in WWTPs. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/41232]  |
| 专题 | 生态环境研究中心_土壤环境科学实验室 |
| 推荐引用方式 GB/T 7714 | Zhao, Yi,Zhu, Yong-Guan,Zhang, Tong,et al. Tracking antibiotic resistome during wastewater treatment using high throughput quantitative PCR[J]. ENVIRONMENT INTERNATIONAL,2018,117:146-153. |
| APA | Zhao, Yi.,Zhu, Yong-Guan.,Zhang, Tong.,Gillings, Michael R..,Chen, Hong.,...&An, Xin-Li.(2018).Tracking antibiotic resistome during wastewater treatment using high throughput quantitative PCR.ENVIRONMENT INTERNATIONAL,117,146-153. |
| MLA | Zhao, Yi,et al."Tracking antibiotic resistome during wastewater treatment using high throughput quantitative PCR".ENVIRONMENT INTERNATIONAL 117(2018):146-153. |
入库方式： OAI收割
来源：生态环境研究中心
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