Improved matrix pooling
文献类型：期刊论文
| 作者 | Xiong, Wenjun1,2; Ding, Juan1,3; He, Yuanzhen4; Li, Qizhai2
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| 刊名 | STATISTICAL METHODS IN MEDICAL RESEARCH
 |
| 出版日期 | 2019 |
| 卷号 | 28期号:1页码:211-222 |
| 关键词 | Matrix pooling efficiency group testing sensitivity specificity |
| ISSN号 | 0962-2802 |
| DOI | 10.1177/0962280217719914 |
| 英文摘要 | Pooled testing is useful to identify positive specimens for large-scale screening. Matrix pooling is one of the commonly used algorithms. In this work, we investigate the properties of matrix pooling and reveal that the efficiency of matrix pooling is related with the magnitude of overlapping among groups. Based on this property, we develop a new design to further improve the efficiency while taking into account of testing error. The efficiency, pooling sensitivity and specificity of this algorithm are explicitly derived and verified through plasmode simulation of detecting acute human immunodeficiency virus among patients who were suspected to have malaria in rural Ugandan. We show that the new design outperforms matrix pooling in efficiency while retain the pooling sensitivity and specificity. |
| 资助项目 | National Natural Science Foundation of China[11526061] ; National Natural Science Foundation of China[11501134] ; National Natural Science Foundation of China[11371353] ; Guangxi Natural Science Foundation[2015GXNSFBA139016] ; key project of Guangxi Normal University[2014ZD002] ; Program on the High Level Innovation Team and Outstanding Scholars in Universities of Guangxi Province ; Special National Key Research and Development Plan[2016YFD0400206] ; Breakthrough Projects of Strategic Priority Program of the Chinese Academy of Sciences[XDB13040600] |
| WOS研究方向 | Health Care Sciences & Services ; Mathematical & Computational Biology ; Medical Informatics ; Mathematics |
| 语种 | 英语 |
| WOS记录号 | WOS:000454598800014 |
| 出版者 | SAGE PUBLICATIONS LTD |
| 源URL | [http://ir.amss.ac.cn/handle/2S8OKBNM/32063]  |
| 专题 | 系统科学研究所 |
| 通讯作者 | Xiong, Wenjun |
| 作者单位 | 1.Guangxi Normal Univ, Sch Math & Stat, Guilin, Peoples R China 2.Chinese Acad Sci, Acad Math & Syst Sci, Beijing, Peoples R China 3.Vanderbilt Univ, Sch Med, Dept Med, Nashville, TN 37212 USA 4.Beijing Normal Univ, Sch Math Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xiong, Wenjun,Ding, Juan,He, Yuanzhen,et al. Improved matrix pooling[J]. STATISTICAL METHODS IN MEDICAL RESEARCH,2019,28(1):211-222. |
| APA | Xiong, Wenjun,Ding, Juan,He, Yuanzhen,&Li, Qizhai.(2019).Improved matrix pooling.STATISTICAL METHODS IN MEDICAL RESEARCH,28(1),211-222. |
| MLA | Xiong, Wenjun,et al."Improved matrix pooling".STATISTICAL METHODS IN MEDICAL RESEARCH 28.1(2019):211-222. |
入库方式： OAI收割
来源：数学与系统科学研究院
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