中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 过程工程研究所
  3. 中国科学院过程工程研究所
Light-Activated Nanoparticles Encapsulated with Santalum Album: A Potential Therapeutic Agent for Neurodegenerative Disease

文献类型：期刊论文

作者Zhang, Tianlu1; Li, Jian2,3,4; Zhang, Mengying2,3; Lu, Zhiguo1,6; Wang, Zhen1; Shen, Jie1,6; Hu, Jing7,8; Niu, Yunwei7,8; Xiao, Zuobing7,8; Chen, Lei5
刊名NANOSCIENCE AND NANOTECHNOLOGY LETTERS
出版日期2019-03-01
卷号11期号:3页码:312-321
关键词Mesoporous Silica Nanocolumns Fragrance Light-Activated Release Wallpaper Azobenzene Derivatives
ISSN号1941-4900
DOI10.1166/nnl.2019.2899
英文摘要Sandela 803 is a cheap representative synthetic santalum essential oil that has therapeutic effects on neurodegenerative diseases. With development of nanotechnology, many types of nanomaterials loaded with fragrances could regulate release rate of aroma. However, most of them rely on destruction of interaction between fragrances and nanocarriers. These release processes are irreversible and un-sustained. In this study, light-activated mesoporous silica nanocolumns loaded with sandela 803 were designed, prepared and applied to wallpaper. The azobenzene derivatives modified with pore wall served as gatekeepers in the dark, and prevented guest molecules from escaping. By contrast, the azobenzene derivatives acted as brooms for impelling the sandela 803 from the mesoporous in the light. The structures and performances of light-activated mesoporous silica nanocolumns were quite stable during the release process. The release of sandela 803 was thus sustained and controlled. This kind of nano-fragrance with abilities of sustained and controlled release is expected to be used in the treatment of neurodegenerative diseases.
WOS关键词MESOPOROUS SILICA ; NANOCOMPOSITE ; ELECTRODE ; MICELLES ; DELIVERY ; INHIBITION ; FRAMEWORK ; CURCUMIN ; REMOVAL ; DRUG
资助项目National High Technology Research and Development Program[2016YFA0200303] ; Beijing Natural Science Foundation[L172046] ; Beijing Natural Science Foundation[2192057] ; National Natural Science Foundation of China[31522023] ; National Natural Science Foundation of China[31771095] ; National Natural Science Foundation of China[21875254] ; National Natural Science Foundation of China[51573188] ; Beijing Municipal Science and Technology Commission[Z161100002616015]
WOS研究方向Science & Technology - Other Topics ; Materials Science ; Physics
语种英语
WOS记录号WOS:000467946500002
出版者AMER SCIENTIFIC PUBLISHERS
资助机构National High Technology Research and Development Program ; Beijing Natural Science Foundation ; National Natural Science Foundation of China ; Beijing Municipal Science and Technology Commission
源URL[http://ir.ipe.ac.cn/handle/122111/28303]  
专题中国科学院过程工程研究所
通讯作者Chen, Lei; Mansmann, Ulrich R.; Zhang, Xin
作者单位1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Ludwig Maximilians Univ Munchen, Inst Med Informat Biometry & Epidemiol, D-81377 Munich, Germany
3.German Canc Consortium DKTK, D-81377 Heidelberg, Germany
4.German Canc Res Ctr, D-81377 Heidelberg, Germany
5.Navy Gen Hosp People Liberat Army, Dept Obstet & Gynecol, Beijing 100048, Peoples R China
6.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
7.Shanghai Res Inst Fragrance & Flavor Ind, Shanghai 200232, Peoples R China
8.Shanghai Inst Technol, Sch Perfume & Aroma Technol, Shanghai 200233, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Tianlu,Li, Jian,Zhang, Mengying,et al. Light-Activated Nanoparticles Encapsulated with Santalum Album: A Potential Therapeutic Agent for Neurodegenerative Disease[J]. NANOSCIENCE AND NANOTECHNOLOGY LETTERS,2019,11(3):312-321.
APA Zhang, Tianlu.,Li, Jian.,Zhang, Mengying.,Lu, Zhiguo.,Wang, Zhen.,...&Zhang, Xin.(2019).Light-Activated Nanoparticles Encapsulated with Santalum Album: A Potential Therapeutic Agent for Neurodegenerative Disease.NANOSCIENCE AND NANOTECHNOLOGY LETTERS,11(3),312-321.
MLA Zhang, Tianlu,et al."Light-Activated Nanoparticles Encapsulated with Santalum Album: A Potential Therapeutic Agent for Neurodegenerative Disease".NANOSCIENCE AND NANOTECHNOLOGY LETTERS 11.3(2019):312-321.

入库方式： OAI收割

来源：过程工程研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。