Fabrication of Multilayered Molecularly Imprinted Membrane for Selective Recognition and Separation of Artemisinin
文献类型：期刊论文
| 作者 | Zhang, YQ; Tan, X; Liu, X; Li, CS; Zeng, SJ; Wang, H; Zhang, SJ; Zhang, Yongqiang; Tan, Xin; Liu, Xiao |
| 刊名 | ACS SUSTAINABLE CHEMISTRY & ENGINEERING
 |
| 出版日期 | 2019 |
| 卷号 | 7期号:3页码:3127 |
| 关键词 | Artemisinin ANNUA L. Molecularly imprinted membrane ASSISTED EXTRACTION Chitosan PURIFICATION Permselectivity SILICA COPOLYMERS PARTICLES SOLVENT ACID ATRP |
| ISSN号 | 2168-0485 |
| DOI | 10.1021/acssuschemeng.8b04908 |
| 文献子类 | Article |
| 英文摘要 | Molecularly imprinted membranes with multifunctional layers for artemisinin separation and purification were fabricated on porous chitosan membranes. The molecularly imprinted layer was fabricated through an in situ activator generated by electron transfer atom transfer radical polymerization method by using artemisinin as the templet molecule. Properties of the prepared materials were characterized by SEM, IR, XPS, EDS, AFM, etc. Adsorption ability and dynamics, permeation capacity, and reusability have been investigated. Results indicate that this kind of molecularly imprinted membrane possesses desirable adsorption ability for artemisinin (18.89 mg/g) and permselectivity factors (beta) as high as 2.15 and 2.03 toward artemether and artesunate, respectively. Mechanism of selective adsorption and permeation was unveiled by molecular simulation, which indicates that the tailor-made recognition sites on the membrane possess higher interaction force toward artemisinin than artemether or artesunate, resulting in artemisinin adsorption by the membrane and separation of this drug from its analogues. The method developed here provides an environmental friendly and sustainable technology for separation and purification of natural products. |
| WOS记录号 | WOS:000458086100031 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/28341]  |
| 专题 | 中国科学院过程工程研究所 |
| 推荐引用方式 GB/T 7714 | Zhang, YQ,Tan, X,Liu, X,et al. Fabrication of Multilayered Molecularly Imprinted Membrane for Selective Recognition and Separation of Artemisinin[J]. ACS SUSTAINABLE CHEMISTRY & ENGINEERING,2019,7(3):3127, 3137. |
| APA | Zhang, YQ.,Tan, X.,Liu, X.,Li, CS.,Zeng, SJ.,...&Zhang, Suojiang.(2019).Fabrication of Multilayered Molecularly Imprinted Membrane for Selective Recognition and Separation of Artemisinin.ACS SUSTAINABLE CHEMISTRY & ENGINEERING,7(3),3127. |
| MLA | Zhang, YQ,et al."Fabrication of Multilayered Molecularly Imprinted Membrane for Selective Recognition and Separation of Artemisinin".ACS SUSTAINABLE CHEMISTRY & ENGINEERING 7.3(2019):3127. |
入库方式： OAI收割
来源：过程工程研究所
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