The Application of Multi-Walled Carbon Nanotubes in Bone Tissue Repair Hybrid Scaffolds and the Effect on Cell Growth In Vitro
文献类型：期刊论文
| 作者 | Xu, Jie1; Hu, Xueyan1; Jiang, Siyu1; Wang, Yiwei2; Parungao, Roxanne2; Zheng, Shuangshuang3; Nie, Yi3,4; Liu, Tianqing1; Song, Kedong1 |
| 刊名 | POLYMERS
 |
| 出版日期 | 2019-02-01 |
| 卷号 | 11期号:2页码:16 |
| 关键词 | MWCNTs CS/Gel/nHAp bone tissue engineering MC3T3-E1 cells |
| DOI | 10.3390/polym11020230 |
| 英文摘要 | In this study, composite scaffolds with different multi-walled carbon nanotubes (MWCNTs) content were prepared by freeze-drying. These scaffolds were characterized by scanning electron microscope (SEM), energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FTIR), porosity, hydrophilicity, mechanical strength, and degradation. The MWCNTs scaffolds were structurally sound and had porous structures that offered ample space for adherence, proliferation, and differentiation of MC3T3-E1 cells, and also supported the transport of nutrients and metabolic waste. CS/Gel/nHAp/0.3%MWCNTs scaffolds provided the best outcomes in terms of scaffold porosity, hydrophilicity, and degradation rate. However, CS/Gel/nHAp/0.6%MWCNTs scaffolds were found to support the optimal growth, homogenous distribution, and biological activity of MC3T3-E1 cells. The excellent properties of CS/Gel/nHAp/0.6%MWCNTs scaffolds for the adhesion, proliferation, and osteogenesis differentiation of MC3T3-E1 cells in vitro highlights the potential applications of this scaffold in bone tissue regeneration. |
| WOS关键词 | COMPOSITE SCAFFOLD ; AUTOLOGOUS BONE ; GELATIN ; CHITOSAN ; HYDROXYAPATITE ; MICROSPHERES ; FABRICATION ; HYDROGEL ; MICROSTRUCTURE ; REGENERATION |
| 资助项目 | National Natural Science Foundation of China[31670978/21676041] ; Fok Ying Tung Education Foundation[132027] ; State Key Laboratory of Fine Chemicals[KF1111] ; Natural Science Foundation of Liaoning[20180510028] |
| WOS研究方向 | Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000460296000044 |
| 出版者 | MDPI |
| 资助机构 | National Natural Science Foundation of China ; Fok Ying Tung Education Foundation ; State Key Laboratory of Fine Chemicals ; Natural Science Foundation of Liaoning |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/28349]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Nie, Yi; Liu, Tianqing; Song, Kedong |
| 作者单位 | 1.Dalian Univ Technol, Dalian R&D Ctr Stem Cell & Tissue Engn, State Key Lab Fine Chem, Dalian 116024, Peoples R China 2.Univ Sydney, ANZAC Res Inst, Burns Res Grp, Sydney, NSW 2139, Australia 3.Zhengzhou Inst Emerging Ind Technol, Zhengzhou 450000, Henan, Peoples R China 4.Chinese Acad Sci, Inst Proc Engn, Key Lab Green Proc & Engn, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Jie,Hu, Xueyan,Jiang, Siyu,et al. The Application of Multi-Walled Carbon Nanotubes in Bone Tissue Repair Hybrid Scaffolds and the Effect on Cell Growth In Vitro[J]. POLYMERS,2019,11(2):16. |
| APA | Xu, Jie.,Hu, Xueyan.,Jiang, Siyu.,Wang, Yiwei.,Parungao, Roxanne.,...&Song, Kedong.(2019).The Application of Multi-Walled Carbon Nanotubes in Bone Tissue Repair Hybrid Scaffolds and the Effect on Cell Growth In Vitro.POLYMERS,11(2),16. |
| MLA | Xu, Jie,et al."The Application of Multi-Walled Carbon Nanotubes in Bone Tissue Repair Hybrid Scaffolds and the Effect on Cell Growth In Vitro".POLYMERS 11.2(2019):16. |
入库方式： OAI收割
来源：过程工程研究所
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