中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Peptide-modulated self-assembly as a versatile strategy for tumor supramolecular nanotheranostics

文献类型:期刊论文

作者Li, Shukun1,3; Zou, Qianli1; Xing, Ruirui1; Govindaraju, Thimmaiah4; Fakhrullin, Rawil5; Yan, Xuehai1,2,3
刊名THERANOSTICS
出版日期2019
卷号9期号:11页码:3249-3261
关键词peptides self-assembly intermolecular interactions nanotheranostics cancer
ISSN号1838-7640
DOI10.7150/thno.31814
英文摘要Advances in supramolecular self-assembly have promoted the development of theranostics, the combination of both therapeutic and diagnostic functions in a single nanoplatform, which is closely associated with antitumor applications and has shown promising potential in personalized medicine. Peptide-modulated self-assembly serves as a versatile strategy for tumor supramolecular nanotheranostics possessing controllability, programmability, functionality and biosafety, thus promoting the translation of nanotheranostics from bench to bedside. In this review, we will focus on the self-assembly of peptide-photosensitizers and peptide-drugs as well as multicomponent cooperative self-assembly for the fabrication of nanotheranostics that integrate diagnosis and therapeutics for antitumor applications. Emphasis will be placed on building block design, interaction strategies and the potential relationships between their structures and properties, aiming to increase understanding of the critical role of peptide-modulated self-assembly in advancing antitumor supramolecular nanotheranostics.
WOS关键词AMYLOID-BETA ; NANOPARTICLES ; PROGRESS ; DESIGN ; NANOSTRUCTURES ; HYDROGELS ; DELIVERY ; THERAPY ; CELL ; PHOTOSENSITIZERS
资助项目National Natural Science Foundation of China[21773248] ; National Natural Science Foundation of China[21802144] ; National Natural Science Fund BRICS STI Framework Programme[51861145304] ; Innovation Research Community Science Fund[21821005] ; Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (CAS)[QYZDB-SSW-JSC034]
WOS研究方向Research & Experimental Medicine
语种英语
WOS记录号WOS:000468203100013
出版者IVYSPRING INT PUBL
资助机构National Natural Science Foundation of China ; National Natural Science Fund BRICS STI Framework Programme ; Innovation Research Community Science Fund ; Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (CAS)
源URL[http://ir.ipe.ac.cn/handle/122111/28357]  
专题中国科学院过程工程研究所
通讯作者Yan, Xuehai
作者单位1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Ctr Mesosci, Inst Proc Engn, Beijing 100190, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Jawaharlal Nehru Ctr Adv Sci Res, New Chem Unit, Bioorgan Chem Lab, Jakkur PO, Bengaluru 560064, Karnataka, India
5.Kazan Fed Univ, Inst Fundamental Med & Biol, Bionanotechnol Lab, Kazan 420008, Republic Of Tat, Russia
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GB/T 7714
Li, Shukun,Zou, Qianli,Xing, Ruirui,et al. Peptide-modulated self-assembly as a versatile strategy for tumor supramolecular nanotheranostics[J]. THERANOSTICS,2019,9(11):3249-3261.
APA Li, Shukun,Zou, Qianli,Xing, Ruirui,Govindaraju, Thimmaiah,Fakhrullin, Rawil,&Yan, Xuehai.(2019).Peptide-modulated self-assembly as a versatile strategy for tumor supramolecular nanotheranostics.THERANOSTICS,9(11),3249-3261.
MLA Li, Shukun,et al."Peptide-modulated self-assembly as a versatile strategy for tumor supramolecular nanotheranostics".THERANOSTICS 9.11(2019):3249-3261.

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来源:过程工程研究所

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