Gap-Tethered Au@AgAu Raman Tags for the Ratiometric Detection of MC-LR
文献类型：期刊论文
| 作者 | Zhao, Yuan1; Zheng, Fangjie1; Ke, Wei1; Zhang, Wei2 ; Shi, Lixia1; Liu, Han1
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| 刊名 | ANALYTICAL CHEMISTRY
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| 出版日期 | 2019-06-04 |
| 卷号 | 91期号:11页码:7162-7172 |
| ISSN号 | 0003-2700 |
| DOI | 10.1021/acs.analchem.9b00348 |
| 通讯作者 | Zhao, Yuan(zhaoyuan@jiangnan.edu.cn) |
| 英文摘要 | Establishing a simple and accurate assay for detecting Microcystin-LR (MC-LR) is of significant important for the environment and human health. Herein, we develop a ratiometric surface-enhanced Raman scattering (SERS) apta-sensor based on internal standard (IS) methods for the sensitive and reproducible quantitative detection of MC-LR Gap-tethered SERS-active Au@AgAu nanoparticles (NPs) are successfully prepared and the gap sizes are adjustable by simply adjusting the acidity. Gap-tethered Au@AgAu NPs exhibit gap tunable amplified SERS activity and are served as SERS tags. The graphene oxide (GO)/Fe3O4 NPs demonstrate a unique and stable Raman band from the graphitic component, making them an ideal IS for quantitative Raman analysis. In principle, Au@gap@AgAu NPs are assembled with GO/Fe3O4 NPs depending on the pi-pi stacking interaction between GO and MC-LR aptamers. In the presence of MC-LR, Au@gap@AgAu NPs are dissociated from GO/Fe3O4 NPs due to the affinity of aptamer, leading to the changes of Raman intensity of SERS tags. Quantitatively, upon correction by the IS Raman signals, the limit of detection (LOD) is as low as 9.82 pM for MC-LR The developed protocol provides a simple and rapid approach for the sensitive and quantitative detection of MC-LR and shows great promise for applications in complex systems. |
| 资助项目 | National Key Research and Development Program of China[2017YFC1601706] ; Natural Science Foundation of Jiangsu Province[BK20171136] ; National First-class Discipline Program of Food Science and Technology[JUFSTR20180302] ; National Natural Science Foundation of China[61575196] ; 111 Project[B13025] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000470793800032 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/8118]  |
| 专题 | 科研公共服务平台 |
| 通讯作者 | Zhao, Yuan |
| 作者单位 | 1.Jiangnan Univ, Sch Chem & Mat Engn, Minist Educ, Key Lab Synthet & Biol Colloids, Wuxi 214122, Jiangsu, Peoples R China 2.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Yuan,Zheng, Fangjie,Ke, Wei,et al. Gap-Tethered Au@AgAu Raman Tags for the Ratiometric Detection of MC-LR[J]. ANALYTICAL CHEMISTRY,2019,91(11):7162-7172. |
| APA | Zhao, Yuan,Zheng, Fangjie,Ke, Wei,Zhang, Wei,Shi, Lixia,&Liu, Han.(2019).Gap-Tethered Au@AgAu Raman Tags for the Ratiometric Detection of MC-LR.ANALYTICAL CHEMISTRY,91(11),7162-7172. |
| MLA | Zhao, Yuan,et al."Gap-Tethered Au@AgAu Raman Tags for the Ratiometric Detection of MC-LR".ANALYTICAL CHEMISTRY 91.11(2019):7162-7172. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
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