中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae)

文献类型:期刊论文

作者Li, Kexin1,3; Geng, Jianing2; Qu, Jiapeng3; Zhang, Yanming1; Hu, Songnian2
刊名BMC GENETICS
出版日期2010-11-10
卷号11
ISSN号1471-2156
文献子类Article
英文摘要Background: The plateau pika (Ochotona curzoniae) is an underground-dwelling mammal, native to the Tibetan plateau of China. A set of 10 polymorphic microsatellite loci has been developed earlier. Its reliability for parentage assignment has been tested in a plateau pika population. Two family groups with a known pedigree were used to validate the power of this set of markers. Results: The error in parentage assignment using a combination of these 10 loci was very low as indicated by their power of discrimination (0.803 - 0.932), power of exclusion (0.351 - 0.887), and an effectiveness of the combined probability of exclusion in parentage assignment of 99.999%. Conclusion: All the offspring of a family could be assigned to their biological mother; and their father or relatives could also be identified. This set of markers therefore provides a powerful and efficient tool for parentage assignment and other population analyses in the plateau pika.; Background: The plateau pika (Ochotona curzoniae) is an underground-dwelling mammal, native to the Tibetan plateau of China. A set of 10 polymorphic microsatellite loci has been developed earlier. Its reliability for parentage assignment has been tested in a plateau pika population. Two family groups with a known pedigree were used to validate the power of this set of markers.
WOS关键词DNA MARKERS ; ASSIGNMENT ; PATERNITY ; LOCI ; POPULATIONS
WOS研究方向Genetics & Heredity
语种英语
WOS记录号WOS:000284752300001
公开日期2011-12-13
源URL[http://ir.nwipb.ac.cn//handle/363003/1626]  
专题西北高原生物研究所_中国科学院西北高原生物研究所
作者单位1.Chinese Acad Sci, Key Lab Adaptat & Evolut Plateau Biota, NW Inst Plateau Biol, Xining 810001, Qinghai, Peoples R China
2.Chinese Acad Sci, Key Lab Genome Informat & Sci, Beijing Inst Genom, Beijing 100029, Peoples R China
3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Li, Kexin,Geng, Jianing,Qu, Jiapeng,et al. Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae)[J]. BMC GENETICS,2010,11.
APA Li, Kexin,Geng, Jianing,Qu, Jiapeng,Zhang, Yanming,&Hu, Songnian.(2010).Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae).BMC GENETICS,11.
MLA Li, Kexin,et al."Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae)".BMC GENETICS 11(2010).

入库方式: OAI收割

来源:西北高原生物研究所

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