Thermoresponsive Oligo(ethylene glycol)-Based Polymer Brushes on Polymer Monoliths for All-Aqueous Chromatography
文献类型：期刊论文
| 作者 | Li, Nan1,2; Qi, Li1; Shen, Ying1,2; Li, Yaping1,2; Chen, Yi1 |
| 刊名 | ACS APPLIED MATERIALS & INTERFACES
 |
| 出版日期 | 2013-12-11 |
| 卷号 | 5期号:23页码:12441-12448 |
| 关键词 | Poly(2-(2-methoxyethoxy)Ethyl Methacrylate-co-oligo(Ethylene Glycol) Methacrylate) Brushes Two-step Atom Transfer Radical Polymerization Thermoresponsive Monolith Separation Hydrophobic Interaction |
| ISSN号 | 1944-8244 |
| DOI | 10.1021/am403510g |
| 英文摘要 | Porous polymer monoliths onto which were grafted a thermoresponsive copolymer, poly(2-(2-methoxyethoxy)ethyl methacrylate (MEO(2)MA)-co-oligo(ethylene glycol) methacrylate (OEGMA)), were synthesized by the two-step atom transfer radical polymerization (ATRP) method. The copolymer-grafted monoliths were characterized by elemental analysis, scanning electron microscopy, and mercury intrusion porosimetry. They were further used as the thermoresponsive stationary phase for all-aqueous high-performance liquid chromatography (HPLC). The chromatograms of three steroids demonstrated that the chain length of the grafted copolymer, which was regulated by varying the grafting time, could affect the separation by providing different amounts of hydrophobic interaction sites with analytes. Additionally, the elution profiles of steroids on the stationary phase could also be tuned by the comonomer composition. The results showed that the porous polymer monoliths enabled separation of the test mixture in pure aqueous mobile phase under isocratic conditions. Furthermore, the proposed method provides a simple and promising tool in the design and construction of responsive surfaces for chromatography applications. |
| 语种 | 英语 |
| WOS记录号 | WOS:000328439600031 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/41996]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Qi, Li |
| 作者单位 | 1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Analyt Chem Living Biosyst, Inst Chem, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Nan,Qi, Li,Shen, Ying,et al. Thermoresponsive Oligo(ethylene glycol)-Based Polymer Brushes on Polymer Monoliths for All-Aqueous Chromatography[J]. ACS APPLIED MATERIALS & INTERFACES,2013,5(23):12441-12448. |
| APA | Li, Nan,Qi, Li,Shen, Ying,Li, Yaping,&Chen, Yi.(2013).Thermoresponsive Oligo(ethylene glycol)-Based Polymer Brushes on Polymer Monoliths for All-Aqueous Chromatography.ACS APPLIED MATERIALS & INTERFACES,5(23),12441-12448. |
| MLA | Li, Nan,et al."Thermoresponsive Oligo(ethylene glycol)-Based Polymer Brushes on Polymer Monoliths for All-Aqueous Chromatography".ACS APPLIED MATERIALS & INTERFACES 5.23(2013):12441-12448. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。