Specific Capture and Release of Circulating Tumor Cells Using Aptamer-Modified Nanosubstrates
文献类型：期刊论文
| 作者 | Shen, Qinglin1,2; Xu, Li3; Zhao, Libo2,3; Wu, Dongxia2; Fan, Yunshan2; Zhou, Yiliang2; OuYang, Wei-Han2; Xu, Xiaochun2; Zhang, Zhen3; Song, Min2 |
| 刊名 | ADVANCED MATERIALS
 |
| 出版日期 | 2013-04-24 |
| 卷号 | 25期号:16页码:2368-2373 |
| 关键词 | Cancer Diagnosis Circulating Tumor Cells Nanostructured Materials Aptamer Cell Capture Cell Release |
| ISSN号 | 0935-9648 |
| DOI | 10.1002/adma.201300082 |
| 英文摘要 | A platform for capture and release of circulating tumor cells (CTCs) is demonstrated by utilizing aptamer grafted silicon nanowires. Here, single-stranded DNA-aptamers are generated via the Cell-SELEX process to serve as capture agents, allowing specific capture and release of non-small cell lung cancer (NSCLC) CTCs from whole-blood samples with minimum contamination and negligible disruption to CTC viability and functions. |
| 语种 | 英语 |
| WOS记录号 | WOS:000318040600020 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/42003]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Xiong, Bin |
| 作者单位 | 1.Wuhan Univ, Zhongnan Hosp, Hubei Key Lab Tumor Biol Behav, Dept Oncol,Hubei Canc Clin Study Ctr, Wuhan 430071, Hubei, Peoples R China 2.Univ Calif Los Angeles, Calif NanoSyst Inst CNSI, Crump Inst Mol Imaging CIMI, Dept Mol & Med Pharmacol, Los Angeles, CA 90095 USA 3.Chinese Acad Sci, Inst Chem, Key Lab Mol Nanostruct & Nanotechnol, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shen, Qinglin,Xu, Li,Zhao, Libo,et al. Specific Capture and Release of Circulating Tumor Cells Using Aptamer-Modified Nanosubstrates[J]. ADVANCED MATERIALS,2013,25(16):2368-2373. |
| APA | Shen, Qinglin.,Xu, Li.,Zhao, Libo.,Wu, Dongxia.,Fan, Yunshan.,...&Fang, Xiaohong.(2013).Specific Capture and Release of Circulating Tumor Cells Using Aptamer-Modified Nanosubstrates.ADVANCED MATERIALS,25(16),2368-2373. |
| MLA | Shen, Qinglin,et al."Specific Capture and Release of Circulating Tumor Cells Using Aptamer-Modified Nanosubstrates".ADVANCED MATERIALS 25.16(2013):2368-2373. |
入库方式： OAI收割
来源：化学研究所
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