中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Facile one-pot synthesis of L-proline-stabilized fluorescent gold nanoclusters and its application as sensing probes for serum iron

文献类型:期刊论文

作者Mu, Xiaoyu1,2; Qi, Li1; Dong, Ping3,4; Qiao, Juan1; Hou, Jian1,2; Nie, Zongxiu1; Ma, Huimin1
刊名BIOSENSORS & BIOELECTRONICS
出版日期2013-11-15
卷号49页码:249-255
关键词L-proline Gold Nanocluster Fluorescence Ferric Ion Serum Iron
ISSN号0956-5663
DOI10.1016/j.bios.2013.05.019
英文摘要Gold nanoclusters (Au NCs) possess outstanding physical and chemical attributes that make them excellent scaffolds for the construction of novel chemical and biological sensors. In this study, a simple one-pot synthesis method, employing L-proline as the stabilizer, was presented for preparation of fluorescent Au NCs. This strategy allowed the generation of water-soluble Au NCs within a short time of 15 min. The as-prepared Au NCs exhibited a bluish fluorescence emission at 440 nm and a quantum yield of 2.94%. Based on the aggregation-induced fluorescence quenching mechanism, the Au NCs provided favorable biocompatibility, high sensitivity and good selectivity for the measurement of ferric ion (Fe3+). Furthermore, serum samples were analyzed for the serum iron contents by using this proposed biocompatible fluorescent sensor, indicating the potential value of this Au NCs-based fluorescent sensor for application in biological and clinical analysis. (C) 2013 Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000323396700038
出版者ELSEVIER ADVANCED TECHNOLOGY
源URL[http://ir.iccas.ac.cn/handle/121111/42015]  
专题中国科学院化学研究所
通讯作者Qi, Li
作者单位1.Chinese Acad Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
3.Chinese Acad Med Sci, Plast Surg Hosp, Res Ctr, Beijing 100144, Peoples R China
4.Peking Union Med Coll, Beijing 100144, Peoples R China
推荐引用方式
GB/T 7714
Mu, Xiaoyu,Qi, Li,Dong, Ping,et al. Facile one-pot synthesis of L-proline-stabilized fluorescent gold nanoclusters and its application as sensing probes for serum iron[J]. BIOSENSORS & BIOELECTRONICS,2013,49:249-255.
APA Mu, Xiaoyu.,Qi, Li.,Dong, Ping.,Qiao, Juan.,Hou, Jian.,...&Ma, Huimin.(2013).Facile one-pot synthesis of L-proline-stabilized fluorescent gold nanoclusters and its application as sensing probes for serum iron.BIOSENSORS & BIOELECTRONICS,49,249-255.
MLA Mu, Xiaoyu,et al."Facile one-pot synthesis of L-proline-stabilized fluorescent gold nanoclusters and its application as sensing probes for serum iron".BIOSENSORS & BIOELECTRONICS 49(2013):249-255.

入库方式: OAI收割

来源:化学研究所

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