Facile one-pot synthesis of L-proline-stabilized fluorescent gold nanoclusters and its application as sensing probes for serum iron
文献类型:期刊论文
作者 | Mu, Xiaoyu1,2; Qi, Li1; Dong, Ping3,4; Qiao, Juan1; Hou, Jian1,2; Nie, Zongxiu1; Ma, Huimin1 |
刊名 | BIOSENSORS & BIOELECTRONICS
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出版日期 | 2013-11-15 |
卷号 | 49页码:249-255 |
关键词 | L-proline Gold Nanocluster Fluorescence Ferric Ion Serum Iron |
ISSN号 | 0956-5663 |
DOI | 10.1016/j.bios.2013.05.019 |
英文摘要 | Gold nanoclusters (Au NCs) possess outstanding physical and chemical attributes that make them excellent scaffolds for the construction of novel chemical and biological sensors. In this study, a simple one-pot synthesis method, employing L-proline as the stabilizer, was presented for preparation of fluorescent Au NCs. This strategy allowed the generation of water-soluble Au NCs within a short time of 15 min. The as-prepared Au NCs exhibited a bluish fluorescence emission at 440 nm and a quantum yield of 2.94%. Based on the aggregation-induced fluorescence quenching mechanism, the Au NCs provided favorable biocompatibility, high sensitivity and good selectivity for the measurement of ferric ion (Fe3+). Furthermore, serum samples were analyzed for the serum iron contents by using this proposed biocompatible fluorescent sensor, indicating the potential value of this Au NCs-based fluorescent sensor for application in biological and clinical analysis. (C) 2013 Elsevier B.V. All rights reserved. |
语种 | 英语 |
WOS记录号 | WOS:000323396700038 |
出版者 | ELSEVIER ADVANCED TECHNOLOGY |
源URL | [http://ir.iccas.ac.cn/handle/121111/42015] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Qi, Li |
作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Chinese Acad Med Sci, Plast Surg Hosp, Res Ctr, Beijing 100144, Peoples R China 4.Peking Union Med Coll, Beijing 100144, Peoples R China |
推荐引用方式 GB/T 7714 | Mu, Xiaoyu,Qi, Li,Dong, Ping,et al. Facile one-pot synthesis of L-proline-stabilized fluorescent gold nanoclusters and its application as sensing probes for serum iron[J]. BIOSENSORS & BIOELECTRONICS,2013,49:249-255. |
APA | Mu, Xiaoyu.,Qi, Li.,Dong, Ping.,Qiao, Juan.,Hou, Jian.,...&Ma, Huimin.(2013).Facile one-pot synthesis of L-proline-stabilized fluorescent gold nanoclusters and its application as sensing probes for serum iron.BIOSENSORS & BIOELECTRONICS,49,249-255. |
MLA | Mu, Xiaoyu,et al."Facile one-pot synthesis of L-proline-stabilized fluorescent gold nanoclusters and its application as sensing probes for serum iron".BIOSENSORS & BIOELECTRONICS 49(2013):249-255. |
入库方式: OAI收割
来源:化学研究所
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