中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Cytophilic/Cytophobic Design of Nanomaterials at Biointerfaces

文献类型:期刊论文

作者Sun, Kang; Liu, Hongliang; Wang, Shutao; Jiang, Lei
刊名SMALL
出版日期2013-05-27
卷号9期号:9-10页码:1444-1448
关键词Biointerfaces Cell Adhesion Cytophilicity Cytophobicity Nanomaterials
ISSN号1613-6810
DOI10.1002/smll.201201667
英文摘要To control interactions between cells and nanomaterials has been a great challenge because numerous nanomaterials have been intensively explored in the fields of biology and medicine. However, current surface modification of nanomaterials is mainly carried out in an empirical way. Herein, a general strategy to tune the surface chemistry of nanomaterials is proposed based on cell affinity, that is, cytophilic or cytophobic. The cell affinity of nanomaterials directly affects cellular response to materials at the very early stage of cellmaterial interactions before other events, such as endocytosis, cell spreading, and cell differentiation, occur. In this Concept, it is suggested that there is a developing library of cytophilic and cytophobic moieties, and how the cell affinity of nanomaterials functions at biointerfaces is discussed by exemplifying several applications, namely therapy, tissue engineering, and biosensors. It is believed that control of the cytophilic/cytophobic property will be helpful in guiding the design of functional nanomaterials for their biomedical applications.
语种英语
WOS记录号WOS:000319076000003
出版者WILEY-V C H VERLAG GMBH
源URL[http://ir.iccas.ac.cn/handle/121111/42022]  
专题中国科学院化学研究所
通讯作者Wang, Shutao
作者单位Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, BNLMS, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Sun, Kang,Liu, Hongliang,Wang, Shutao,et al. Cytophilic/Cytophobic Design of Nanomaterials at Biointerfaces[J]. SMALL,2013,9(9-10):1444-1448.
APA Sun, Kang,Liu, Hongliang,Wang, Shutao,&Jiang, Lei.(2013).Cytophilic/Cytophobic Design of Nanomaterials at Biointerfaces.SMALL,9(9-10),1444-1448.
MLA Sun, Kang,et al."Cytophilic/Cytophobic Design of Nanomaterials at Biointerfaces".SMALL 9.9-10(2013):1444-1448.

入库方式: OAI收割

来源:化学研究所

浏览0
下载0
收藏0
其他版本

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。