Cytophilic/Cytophobic Design of Nanomaterials at Biointerfaces
文献类型：期刊论文
| 作者 | Sun, Kang; Liu, Hongliang; Wang, Shutao; Jiang, Lei |
| 刊名 | SMALL
 |
| 出版日期 | 2013-05-27 |
| 卷号 | 9期号:9-10页码:1444-1448 |
| 关键词 | Biointerfaces Cell Adhesion Cytophilicity Cytophobicity Nanomaterials |
| ISSN号 | 1613-6810 |
| DOI | 10.1002/smll.201201667 |
| 英文摘要 | To control interactions between cells and nanomaterials has been a great challenge because numerous nanomaterials have been intensively explored in the fields of biology and medicine. However, current surface modification of nanomaterials is mainly carried out in an empirical way. Herein, a general strategy to tune the surface chemistry of nanomaterials is proposed based on cell affinity, that is, cytophilic or cytophobic. The cell affinity of nanomaterials directly affects cellular response to materials at the very early stage of cellmaterial interactions before other events, such as endocytosis, cell spreading, and cell differentiation, occur. In this Concept, it is suggested that there is a developing library of cytophilic and cytophobic moieties, and how the cell affinity of nanomaterials functions at biointerfaces is discussed by exemplifying several applications, namely therapy, tissue engineering, and biosensors. It is believed that control of the cytophilic/cytophobic property will be helpful in guiding the design of functional nanomaterials for their biomedical applications. |
| 语种 | 英语 |
| WOS记录号 | WOS:000319076000003 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/42022]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, Shutao |
| 作者单位 | Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, BNLMS, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Kang,Liu, Hongliang,Wang, Shutao,et al. Cytophilic/Cytophobic Design of Nanomaterials at Biointerfaces[J]. SMALL,2013,9(9-10):1444-1448. |
| APA | Sun, Kang,Liu, Hongliang,Wang, Shutao,&Jiang, Lei.(2013).Cytophilic/Cytophobic Design of Nanomaterials at Biointerfaces.SMALL,9(9-10),1444-1448. |
| MLA | Sun, Kang,et al."Cytophilic/Cytophobic Design of Nanomaterials at Biointerfaces".SMALL 9.9-10(2013):1444-1448. |
入库方式： OAI收割
来源：化学研究所
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