Complexation with organometallic ruthenium pharmacophores enhances the ability of 4-anilinoquinazolines inducing apoptosis
文献类型：期刊论文
| 作者 | Zheng, Wei1,2; Luo, Qun1,2; Lin, Yu1,2; Zhao, Yao1,2; Wang, Xiuli3; Du, Zhifeng1,2; Hao, Xiang1; Yu, Yang3; Lu, Shuang1,2; Ji, Liyun1,2 |
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2013 |
| 卷号 | 49期号:87页码:10224-10226 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c3cc43000f |
| 英文摘要 | The complexation with organoruthenium fragments confers 4-anilinoquinazoline pharmacophores with higher potential for inducing cellular apoptosis while the highly inhibitory activity of 4-anilinoquinazolines against EGFR and the reactivity of the ruthenium centre to 9-ethylguanine are well preserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000325643500004 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/42072]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, Fuyi |
| 作者单位 | 1.Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Chem, CAS Key Lab Analyt Chem Living Biosyst, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zheng, Wei,Luo, Qun,Lin, Yu,et al. Complexation with organometallic ruthenium pharmacophores enhances the ability of 4-anilinoquinazolines inducing apoptosis[J]. CHEMICAL COMMUNICATIONS,2013,49(87):10224-10226. |
| APA | Zheng, Wei.,Luo, Qun.,Lin, Yu.,Zhao, Yao.,Wang, Xiuli.,...&Wang, Fuyi.(2013).Complexation with organometallic ruthenium pharmacophores enhances the ability of 4-anilinoquinazolines inducing apoptosis.CHEMICAL COMMUNICATIONS,49(87),10224-10226. |
| MLA | Zheng, Wei,et al."Complexation with organometallic ruthenium pharmacophores enhances the ability of 4-anilinoquinazolines inducing apoptosis".CHEMICAL COMMUNICATIONS 49.87(2013):10224-10226. |
入库方式： OAI收割
来源：化学研究所
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