Bio-inspired soft polystyrene nanotube substrate for rapid and highly efficient breast cancer-cell capture
文献类型：期刊论文
| 作者 | Liu, Xueli1,2; Chen, Li1,2; Liu, Hongliang1; Yang, Gao1,2; Zhang, Pengchao1,2; Han, Dong3; Wang, Shutao1; Jiang, Lei1 |
| 刊名 | NPG ASIA MATERIALS
 |
| 出版日期 | 2013-09-01 |
| 卷号 | 5 |
| 关键词 | Bio-inspired Cancer Diagnosis Cell Capture Nanostructures Polystyrene Soft Polymers |
| ISSN号 | 1884-4049 |
| DOI | 10.1038/am.2013.43 |
| 英文摘要 | The softness of materials is very important in cellular processes, such as cell adhesion, spread, proliferation and differentiation. Using soft materials benefits many biological studies and applications, such as wound healing, tissue engineering and clinical surgery. However, in other areas, such as rare cancer-cell capture and isolation, the importance of the softness of materials has not yet been studied. Extracellular matrix suitable for cell contact and survival is formed from soft materials with specific molecules and nanostructures. Herein, we report a soft polystyrene nanotube substrate inspired by the cell microenvironment that achieves rapid and highly efficient breast cancer-cell capture from whole-blood samples with high cell viability by integrating the soft nature of polystyrene polymer with specific capture agents and surface structures. This study provides a potentially optimal candidate for a high-quality breast cancer-cell detection platform and will provide new prospects for designing cell-material interfaces for advanced cell-based biological studies and clinical applications in the future. |
| 语种 | 英语 |
| WOS记录号 | WOS:000325157800003 |
| 出版者 | NATURE PUBLISHING GROUP |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/42120]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, Shutao |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100190, Peoples R China 3.Natl Ctr NanoSci & Technol, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Xueli,Chen, Li,Liu, Hongliang,et al. Bio-inspired soft polystyrene nanotube substrate for rapid and highly efficient breast cancer-cell capture[J]. NPG ASIA MATERIALS,2013,5. |
| APA | Liu, Xueli.,Chen, Li.,Liu, Hongliang.,Yang, Gao.,Zhang, Pengchao.,...&Jiang, Lei.(2013).Bio-inspired soft polystyrene nanotube substrate for rapid and highly efficient breast cancer-cell capture.NPG ASIA MATERIALS,5. |
| MLA | Liu, Xueli,et al."Bio-inspired soft polystyrene nanotube substrate for rapid and highly efficient breast cancer-cell capture".NPG ASIA MATERIALS 5(2013). |
入库方式： OAI收割
来源：化学研究所
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