PEGylation of fluoridated hydroxyapatite (FAp):Ln(3+) nanorods for cell imaging
文献类型：期刊论文
| 作者 | Zhang, Xiaoyong1; Hui, Junfeng2; Yang, Bin1; Yang, Yong1; Fan, Daidi2; Liu, Meiying3; Tao, Lei1; Wei, Yen1 |
| 刊名 | POLYMER CHEMISTRY
 |
| 出版日期 | 2013 |
| 卷号 | 4期号:15页码:4120-4125 |
| ISSN号 | 1759-9954 |
| DOI | 10.1039/c3py00489a |
| 英文摘要 | PEGylation is a popular approach for the surface functionalization of nanoparticles to achieve improved properties and better performance. Herein, we developed a facile method for surface PEGylation of hydrophobic fluoridated hydroxyapatite (FAp):Ln(3+) (Ln = Eu or Tb) nanorods via hydrophobic interactions between oleic acid and amphiphilic synthetic copolymers, which were synthesized through reversible addition-fragmentation chain transfer (RAFT) polymerization using stearyl methacrylate (SMA) and poly(ethylene glycol) methacrylate (PEGMA) as monomers. Our results demonstrated that the morphology and fluorescent properties of the FAp nanorods are not significantly changed by the PEGylation procedure, and the resulting FAp nanorods were found to be stable in aqueous solution. More importantly, these PEGylated FAp nanorods are biocompatible with cells and could be utilized for cell imaging applications. Therefore, we believe that the method described in this work is a simple, efficient and general strategy for the surface PEGylation of hydrophobic nanoparticles. |
| 语种 | 英语 |
| WOS记录号 | WOS:000321858300006 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/42131]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Tao, Lei |
| 作者单位 | 1.Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China 2.NW Univ Xian, Shaanxi Key Lab Degradable Biomed Mat, Shanxi R&D Ctr Biomat & Fermentat Engn, Sch Chem Engn, Xian 710069, Peoples R China 3.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Key Lab Organ Solids,Lab New Mat, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Xiaoyong,Hui, Junfeng,Yang, Bin,et al. PEGylation of fluoridated hydroxyapatite (FAp):Ln(3+) nanorods for cell imaging[J]. POLYMER CHEMISTRY,2013,4(15):4120-4125. |
| APA | Zhang, Xiaoyong.,Hui, Junfeng.,Yang, Bin.,Yang, Yong.,Fan, Daidi.,...&Wei, Yen.(2013).PEGylation of fluoridated hydroxyapatite (FAp):Ln(3+) nanorods for cell imaging.POLYMER CHEMISTRY,4(15),4120-4125. |
| MLA | Zhang, Xiaoyong,et al."PEGylation of fluoridated hydroxyapatite (FAp):Ln(3+) nanorods for cell imaging".POLYMER CHEMISTRY 4.15(2013):4120-4125. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。